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1.
NPP-669, a prodrug of cidofovir, is highly efficacious against human adenovirus infection in the permissive Syrian hamster model.
Antimicrob Agents Chemother
; : e0048924, 2024 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38775484
2.
NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Mol Pharm
; 20(1): 370-382, 2023 01 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36484496
3.
Identification of Ebselen derivatives as novel SARS-CoV-2 main protease inhibitors: Design, synthesis, biological evaluation, and structure-activity relationships exploration.
Bioorg Med Chem
; 96: 117531, 2023 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37972434
4.
Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses.
Antimicrob Agents Chemother
; 64(11)2020 10 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32816736
5.
Pathology in Permissive Syrian Hamsters after Infection with Species C Human Adenovirus (HAdV-C) Is the Result of Virus Replication: HAdV-C6 Replicates More and Causes More Pathology than HAdV-C5.
J Virol
; 91(10)2017 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28250128
6.
Correction: STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.
PLoS Pathog
; 12(1): e1005392, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26745633
7.
Biographical Feature: William S. M. Wold, Ph.D., 1944-2021.
J Virol
; 95(22): e0118421, 2021 10 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-34549981
8.
STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control.
PLoS Pathog
; 11(8): e1005084, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26291525
9.
Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.
Antimicrob Agents Chemother
; 58(12): 7171-81, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25224011
10.
Inhibitors of nucleotidyltransferase superfamily enzymes suppress herpes simplex virus replication.
Antimicrob Agents Chemother
; 58(12): 7451-61, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25267681
11.
Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters.
Antiviral Res
; 222: 105799, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38190973
12.
Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening.
RSC Med Chem
; 14(10): 2068-2078, 2023 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37859715
13.
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability.
J Med Chem
; 66(23): 16426-16440, 2023 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37992202
14.
Filociclovir is a potent inhibitor of human adenovirus F41.
Antiviral Res
; 208: 105431, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36209985
15.
Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors.
J Med Chem
; 65(24): 16902-16917, 2022 12 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36475694
16.
Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity.
J Med Chem
; 65(19): 13343-13364, 2022 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36107752
17.
Identification of a previously unrecognized promoter that drives expression of the UXP transcription unit in the human adenovirus type 5 genome.
J Virol
; 84(21): 11470-8, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20739525
18.
Adenovirus and Oxaliplatin cooperate as agnostic sensitizers for immunogenic cell death in colorectal carcinoma.
Hum Vaccin Immunother
; 16(3): 636-644, 2020 03 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31584324
19.
Generation and characterization of an Il2rg knockout Syrian hamster model for XSCID and HAdV-C6 infection in immunocompromised patients.
Dis Model Mech
; 13(8)2020 08 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32651192
20.
Drug development against human adenoviruses and its advancement by Syrian hamster models.
FEMS Microbiol Rev
; 43(4): 380-388, 2019 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30916746