Detalles de la búsqueda
1.
Themis: advancing precision oncology through comprehensive molecular subtyping and optimization.
Brief Bioinform
; 25(4)2024 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38833322
2.
MpbPPI: a multi-task pre-training-based equivariant approach for the prediction of the effect of amino acid mutations on protein-protein interactions.
Brief Bioinform
; 24(5)2023 09 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37651610
3.
MetDIT: Transforming and Analyzing Clinical Metabolomics Data with Convolutional Neural Networks.
Anal Chem
; 2024 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38324756
4.
Unraveling the mechanism of ceftaroline-induced allosteric regulation in penicillin-binding protein 2a: insights for novel antibiotic development against methicillin-resistant Staphylococcus aureus.
Antimicrob Agents Chemother
; 67(12): e0089523, 2023 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37971241
5.
Discovery of novel and potent InhA direct inhibitors by ensemble docking-based virtual screening and biological assays.
J Comput Aided Mol Des
; 37(12): 695-706, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37642861
6.
Identification of New Cocrystal Systems with Stoichiometric Diversity of Salicylic Acid Using Thermal Methods.
Pharm Res
; 33(4): 1030-9, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26744333
7.
Experiment and molecular dynamics simulations reveal proanthocyanidin B2 and B3 can inhibit prion aggregation by different mechanisms.
J Biomol Struct Dyn
; 42(5): 2424-2436, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-37144732
8.
Artificial Intelligence in Drug Discovery: A Bibliometric Analysis and Literature Review.
Mini Rev Med Chem
; 2024 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38243944
9.
Synergistic inhibition mechanism of quinazolinone and piperacillin on penicillin-binding protein 2a: a promising approach for combating methicillin-resistant Staphylococcus aureus.
J Biomol Struct Dyn
; : 1-13, 2024 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38497736
10.
Multiscale calculations reveal new insights into the reaction mechanism between KRASG12C and α, ß-unsaturated carbonyl of covalent inhibitors.
Comput Struct Biotechnol J
; 23: 1408-1417, 2024 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38616962
11.
The causal association between obesity and gastric cancer and shared molecular signatures: a large-scale Mendelian randomization and multi-omics analysis.
Front Oncol
; 13: 1091958, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37954072
12.
scCURE identifies cell types responding to immunotherapy and enables outcome prediction.
Cell Rep Methods
; 3(11): 100643, 2023 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37989083
13.
Comparison of spray freeze drying and the solvent evaporation method for preparing solid dispersions of baicalein with Pluronic F68 to improve dissolution and oral bioavailability.
AAPS PharmSciTech
; 12(1): 104-13, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21181514
14.
Phase solubility diagrams and energy surface calculations support the solubility enhancement with low hygroscopicity of Bergenin: 4-Aminobenzamide (1: 1) cocrystal.
Int J Pharm
; 601: 120537, 2021 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33781883
15.
Caffeine as a photoprotective agent for diminishing phototoxicity.
Toxicol Ind Health
; 26(10): 667-70, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20630985
16.
In Vitro Release Study of the Polymeric Drug Nanoparticles: Development and Validation of a Novel Method.
Pharmaceutics
; 12(8)2020 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32759786
17.
Effects of the Glass-Forming Ability and Annealing Conditions on Cocrystallization Behaviors via Rapid Solvent Removal: A Case Study of Voriconazole.
Pharmaceutics
; 12(12)2020 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33327381
18.
Formulation development and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid.
AAPS PharmSciTech
; 10(1): 172-82, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19224372
19.
X-Ray Diffraction and Theoretical Calculation-Supported Formation of Polymorphic Cocrystals Discovered Through Thermal Methods: A Case Study.
J Pharm Sci
; 108(10): 3340-3347, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31145922
20.
Influence of operating temperature and pressure on the polymorphic transition of salmeterol xinafoate in supercritical fluids.
J Pharm Sci
; 97(2): 1025-9, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17497727