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1.
Effects of the inhibition of intestinal P-glycoprotein on aliskiren pharmacokinetics in cynomolgus monkeys.
Biopharm Drug Dispos
; 36(1): 15-33, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25264342
2.
Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.
Nat Struct Mol Biol
; 31(1): 159-169, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38057552
3.
A local QSAR model based on the stability of nitrenium ions to support the ICH M7 expert review on the mutagenicity of primary aromatic amines.
Genes Environ
; 44(1): 10, 2022 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35313995
4.
Theoretical calculation of triazolam hydroxylation and endogenous steroid inhibition in the active site of CYP3A4.
Biochim Biophys Acta
; 1774(2): 223-32, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17204458
5.
Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells.
Drug Metab Lett
; 12(1): 14-23, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29357810
6.
New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery.
Drug Metab Lett
; 10(3): 152-160, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27550199
7.
Helices F-G are important for the substrate specificities of CYP3A7.
Drug Metab Dispos
; 35(3): 484-92, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17178770
8.
CYP3A4 and CYP3A7-mediated carbamazepine 10,11-epoxidation are activated by differential endogenous steroids.
Drug Metab Dispos
; 31(4): 432-8, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12642469
9.
Direct interaction between substrates and endogenous steroids in the active site may change the activity of cytochrome P450 3A4.
Biochemistry
; 42(51): 15068-77, 2003 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-14690416
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