Detalles de la búsqueda
1.
Design, synthesis and biological evaluation of novel quinazoline derivatives as immune checkpoint inhibitors.
Bioorg Med Chem Lett
; 108: 129796, 2024 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38754563
2.
Triptan use in elderly over 65 years and the risk of hospitalization for serious vascular events.
J Headache Pain
; 25(1): 68, 2024 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38671362
3.
Design, synthesis and evaluation the bioactivities of novel 1,3-dimethyl-6-amino-1H-indazole derivatives as anticancer agents.
Bioorg Med Chem
; 90: 117377, 2023 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37352576
4.
Establishment of a method to expose and measure pollution in excised porcine skin with electron paramagnetic resonance spectroscopy.
Ecotoxicol Environ Saf
; 247: 114258, 2022 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36343452
5.
Flavonoids from the peels of Citrus unshiu Markov. and their inhibitory effects on RANKL-induced osteoclastogenesis through the downregulation of c-Fos signaling in vitro.
Bioorg Chem
; 107: 104613, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33485103
6.
Impact of the Astaxanthin, Betanin, and EGCG Compounds on Small Oligomers of Amyloid Aß40 Peptide.
J Chem Inf Model
; 60(3): 1399-1408, 2020 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32105466
7.
New Acetohydrazides Incorporating 2-Oxoindoline and 4-Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity.
Chem Biodivers
; 17(3): e1900670, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-31943757
8.
3-Hydroxyolean-12-en-27-oic Acids Inhibit RANKL-Induced Osteoclastogenesis in Vitro and Inflammation-Induced Bone Loss in Vivo.
Int J Mol Sci
; 21(15)2020 Jul 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32718089
9.
Structure-activity relationship of leucyladenylate sulfamate analogues as leucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target of rapamycin complex 1 (mTORC1).
Bioorg Med Chem
; 27(6): 1099-1109, 2019 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30755350
10.
Novel 3,4-dihydro-4-oxoquinazoline-based acetohydrazides: Design, synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.
Bioorg Chem
; 92: 103202, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31479984
11.
(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity.
J Enzyme Inhib Med Chem
; 34(1): 465-478, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30734614
12.
The Effects of 2',4'-Dihydroxy-6'-methoxy-3',5'- dimethylchalcone from Cleistocalyx operculatus Buds on Human Pancreatic Cancer Cell Lines.
Molecules
; 24(14)2019 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31336786
13.
Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region.
Bioorg Med Chem
; 26(5): 1035-1049, 2018 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29398442
14.
Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors.
Bioorg Med Chem
; 26(12): 3133-3144, 2018 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29705377
15.
N'-[(E)-Arylidene]-2-(2,3-dihydro-3-oxo-4H-1,4-benzoxazin-4-yl)-acetohydrazides: Synthesis and Evaluation of Caspase Activation Activity and Cytotoxicity.
Chem Biodivers
; 15(10): e1800322, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30054973
16.
Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors.
Bioorg Med Chem
; 25(15): 4145-4152, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28625715
17.
Alkaloids from Piper nigrum Exhibit Antiinflammatory Activity via Activating the Nrf2/HO-1 Pathway.
Phytother Res
; 31(4): 663-670, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28185326
18.
Inhibitory effects of compounds from Styrax obassia on NO production.
Bioorg Med Chem Lett
; 25(22): 5087-91, 2015 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26483135
19.
α-Substituted 2-(3-fluoro-4-methylsulfonamidophenyl)acetamides as potent TRPV1 antagonists.
Bioorg Med Chem Lett
; 25(11): 2326-30, 2015 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25937016
20.
α-Methylated simplified resiniferatoxin (sRTX) thiourea analogues as potent and stereospecific TRPV1 antagonists.
Bioorg Med Chem Lett
; 24(12): 2685-8, 2014 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24794110