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1.
A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt.
Bioorg Med Chem Lett
; 30(6): 126967, 2020 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32005415
2.
Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.
Biochim Biophys Acta
; 1860(11 Pt A): 2537-2552, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27474998
3.
The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells.
Kidney Int
; 83(5): 845-54, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23235569
4.
Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice.
J Neuroinflammation
; 10: 50, 2013 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23622116
5.
Regulation of microglia effector functions by tumor necrosis factor signaling.
Glia
; 60(2): 189-202, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21989628
6.
Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease.
Mol Ther
; 19(1): 46-52, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20959812
7.
Parkin deficiency increases vulnerability to inflammation-related nigral degeneration.
J Neurosci
; 28(43): 10825-34, 2008 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-18945890
8.
Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.
PLoS One
; 10(8): e0135257, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26301506
9.
RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity.
PLoS One
; 10(4): e0122942, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25897966
10.
AAV-dominant negative tumor necrosis factor (DN-TNF) gene transfer to the striatum does not rescue medium spiny neurons in the YAC128 mouse model of Huntington's disease.
PLoS One
; 9(5): e96544, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24824433
11.
Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents.
J Med Chem
; 55(10): 4837-46, 2012 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-22533790
12.
The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage.
PLoS One
; 3(1): e1453, 2008 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-18197263
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