Detalles de la búsqueda
1.
Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors.
Bioorg Med Chem Lett
; 19(3): 817-20, 2009 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19111461
2.
Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity.
Mol Cancer Ther
; 6(7): 2012-21, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17620431
3.
A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells.
Cancer Res
; 64(18): 6652-9, 2004 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15374980
4.
Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor.
Biochem Pharmacol
; 78(12): 1438-47, 2009 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19665448
5.
Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib.
Cancer Res
; 68(2): 571-9, 2008 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18199554
6.
Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.
J Med Chem
; 51(15): 4632-40, 2008 Aug 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-18620382
7.
Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2-c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases.
Bioorg Med Chem Lett
; 17(1): 250-4, 2007 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17027260
8.
Orally active 4-amino-5-diarylurea-furo[2,3-d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2.
Bioorg Med Chem Lett
; 17(6): 1773-8, 2007 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17276055
9.
Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase.
Bioorg Med Chem Lett
; 15(15): 3519-23, 2005 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15990302
10.
4-Acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitors.
Bioorg Med Chem Lett
; 14(15): 3907-11, 2004 Aug 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-15225695
Resultados
1 -
10
de 10
1
Próxima >
>>