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1.
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.
Bioorg Med Chem
; 20(18): 5600-15, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22883026
2.
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorption.
Bioorg Med Chem
; 20(15): 4680-92, 2012 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22763369
3.
Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly Potent Testosterone-Suppressive Activity and Excellent Water Solubility.
J Med Chem
; 59(19): 8804-8811, 2016 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-27589480
4.
Discovery of a selective kinase inhibitor (TAK-632) targeting pan-RAF inhibition: design, synthesis, and biological evaluation of C-7-substituted 1,3-benzothiazole derivatives.
J Med Chem
; 56(16): 6478-94, 2013 Aug 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23906342
5.
Establishment of cocrystal cocktail grinding method for rational screening of pharmaceutical cocrystals.
Int J Pharm
; 437(1-2): 162-71, 2012 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22871562
6.
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds.
J Med Chem
; 55(7): 3452-78, 2012 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22376051
7.
Characterization and evaluation of miconazole salts and cocrystals for improved physicochemical properties.
Int J Pharm
; 421(2): 230-6, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21983091
8.
High-throughput cocrystal slurry screening by use of in situ Raman microscopy and multi-well plate.
Int J Pharm
; 399(1-2): 52-9, 2010 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-20696223
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