Detalles de la búsqueda
1.
Factors affecting responsiveness of vadadustat in patients with anemia associated with chronic kidney disease: a post-hoc subgroup analysis of Japanese phase 3 randomized studies.
Clin Exp Nephrol
; 28(5): 391-403, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38530490
2.
Phase 3 Randomized Study Comparing Vadadustat with Darbepoetin Alfa for Anemia in Japanese Patients with Nondialysis-Dependent CKD.
J Am Soc Nephrol
; 32(7): 1779-1790, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-33883252
3.
Efficacy and safety of vadadustat compared with darbepoetin alfa in Japanese anemic patients on hemodialysis: a Phase 3, multicenter, randomized, double-blind study.
Nephrol Dial Transplant
; 36(9): 1731-1741, 2021 08 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-33650630
4.
Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 inhibitor Canagliflozin with SGLT1 and SGLT2.
J Pharmacol Exp Ther
; 358(1): 94-102, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27189972
5.
Changes in glucose-induced plasma active glucagon-like peptide-1 levels by co-administration of sodium-glucose cotransporter inhibitors with dipeptidyl peptidase-4 inhibitors in rodents.
J Pharmacol Sci
; 132(4): 255-261, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27889414
6.
Intestinal Sodium Glucose Cotransporter 1 Inhibition Enhances Glucagon-Like Peptide-1 Secretion in Normal and Diabetic Rodents.
J Pharmacol Exp Ther
; 354(3): 279-89, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26105952
7.
The effect of combined treatment with canagliflozin and teneligliptin on glucose intolerance in Zucker diabetic fatty rats.
J Pharmacol Sci
; 127(4): 456-61, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25892328
8.
Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
Am J Physiol Endocrinol Metab
; 306(11): E1225-38, 2014 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24714398
9.
Analysis of the effect of canagliflozin on renal glucose reabsorption and progression of hyperglycemia in zucker diabetic Fatty rats.
J Pharmacol Exp Ther
; 351(2): 423-31, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25216746
10.
Involvement of heparan sulfate in the renoprotective effects of imidapril, an angiotensin-converting enzyme inhibitor, in diabetic db/db mice.
J Recept Signal Transduct Res
; 34(1): 21-5, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24094140
11.
N-Glucosides as human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitors.
Bioorg Med Chem Lett
; 23(20): 5641-5, 2013 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23999047
12.
C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors.
Bioorg Med Chem
; 21(17): 5561-72, 2013 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23809172
13.
Synthesis and biological evaluation of thiophene-C-glucosides as sodium-dependent glucose cotransporter 2 inhibitors.
Chem Pharm Bull (Tokyo)
; 61(10): 1037-43, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24088695
14.
A phase 3, open-label, single-arm study of vadadustat for anemia in chronic kidney disease for Japanese patients on hemodialysis not receiving erythropoiesis-stimulating agents.
Ther Apher Dial
; 26(1): 45-54, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34115437
15.
Characteristics of Japanese patients with non-dialysis-dependent chronic kidney disease initiating treatment for anemia: a retrospective real-world database study.
Curr Med Res Opin
; 38(12): 2175-2182, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36111421
16.
Vadadustat for anemia in chronic kidney disease patients on peritoneal dialysis: A phase 3 open-label study in Japan.
Ther Apher Dial
; 25(5): 642-653, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-33283981
17.
Correcting Postprandial Hyperglycemia in Zucker Diabetic Fatty Rats With an SGLT2 Inhibitor Restores Glucose Effectiveness in the Liver and Reduces Insulin Resistance in Skeletal Muscle.
Diabetes
; 66(5): 1172-1184, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28246292
18.
Long-term treatment with the Na+-glucose cotransporter inhibitor T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.
Life Sci
; 76(23): 2655-68, 2005 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15792833
19.
Beneficial effects of canagliflozin in combination with pioglitazone on insulin sensitivity in rodent models of obese type 2 diabetes.
PLoS One
; 10(1): e0116851, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25615826
20.
Novel Indole-N-glucoside, TA-1887 As a Sodium Glucose Cotransporter 2 Inhibitor for Treatment of Type 2 Diabetes.
ACS Med Chem Lett
; 5(1): 51-5, 2014 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900773