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1.
Comparative kinase and cancer cell panel profiling of kinase inhibitors approved for clinical use from 2018 to 2020.
Front Oncol
; 12: 953013, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36185300
2.
A theoretical entropy score as a single value to express inhibitor selectivity.
BMC Bioinformatics
; 12: 94, 2011 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-21486481
3.
Structural modeling of JAK1 mutations in T-cell acute lymphoblastic leukemia reveals a second contact site between pseudokinase and kinase domains.
Haematologica
; 101(5): e189-91, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26819051
4.
Bet hedging based cooperation can limit kin selection and form a basis for mutualism.
J Theor Biol
; 280(1): 76-87, 2011 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-21510961
5.
Pharmacological validation of TDO as a target for Parkinson's disease.
FEBS J
; 288(14): 4311-4331, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33471408
6.
4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important.
Bioorg Med Chem Lett
; 20(15): 4507-10, 2010 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20580231
7.
2-Phenyl-9H-purine-6-carbonitrile derivatives as selective cathepsin S inhibitors.
Bioorg Med Chem Lett
; 20(15): 4447-50, 2010 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20594841
8.
Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors.
Bioorg Med Chem Lett
; 20(23): 6890-4, 2010 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21030256
9.
Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: improving selectivity over hERG.
Bioorg Med Chem Lett
; 20(21): 6237-41, 2010 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20843687
10.
6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors.
Bioorg Med Chem Lett
; 20(15): 4350-4, 2010 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20598883
11.
Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.
J Struct Biol X
; 4: 100014, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32647818
12.
High-Throughput Fluorescence-Based Activity Assay for Arginase-1.
SLAS Discov
; 25(9): 1018-1025, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32418491
13.
Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0.
Front Immunol
; 11: 609490, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33584686
14.
The dependency game: multiperson reciprocal sharing leads to stable cooperation which can evolve into group formation.
J Theor Biol
; 260(2): 253-60, 2009 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-19527733
15.
Combined Cellular and Biochemical Profiling to Identify Predictive Drug Response Biomarkers for Kinase Inhibitors Approved for Clinical Use between 2013 and 2017.
Mol Cancer Ther
; 18(2): 470-481, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30381447
16.
TTK Inhibitors as a Targeted Therapy for CTNNB1 (ß-catenin) Mutant Cancers.
Mol Cancer Ther
; 16(11): 2609-2617, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28751540
17.
Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance.
J Mol Biol
; 429(4): 574-586, 2017 02 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-28043854
18.
Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines.
Oncotarget
; 8(24): 38309-38325, 2017 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28415765
19.
Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity.
J Mol Biol
; 429(14): 2211-2230, 2017 07 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28539250
20.
Identification of an evolutionary conserved structural loop that is required for the enzymatic and biological function of tryptophan 2,3-dioxygenase.
Sci Rep
; 6: 39199, 2016 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-27995966