Detalles de la búsqueda
1.
Exploring the mechanism of action of spirooxindoles as a class of CDK2 inhibitors: a structure-based computational approach.
Phys Chem Chem Phys
; 26(22): 16139-16152, 2024 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38787638
2.
Taming the cytokine storm: small molecule inhibitors targeting IL-6/IL-6α receptor.
Mol Divers
; 2024 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38366102
3.
A deep learning-based theoretical protocol to identify potentially isoform-selective PI3Kα inhibitors.
Mol Divers
; 2024 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38305819
4.
Rhodanine-benzamides as potential hits for α-amylase enzyme inhibitors and radical (DPPH and ABTS) scavengers.
Mol Divers
; 2024 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38446373
5.
Structural basis for the mutation-induced dysfunction of the human IL-15/IL-15α receptor complex.
Phys Chem Chem Phys
; 25(4): 3020-3030, 2023 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36607223
6.
Identification of potent anti-immunogenic agents through virtual screening, 3D-QSAR studies, and in vitro experiments.
Mol Divers
; 2023 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37550601
7.
Syntheses, in vitro, and in silico studies of rhodanine-based schiff bases as potential α-amylase inhibitors and radicals (DPPH and ABTS) scavengers.
Mol Divers
; 27(2): 767-791, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35604512
8.
New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights.
J Enzyme Inhib Med Chem
; 38(1): 2281260, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37994663
9.
Multitargeted inhibition of key enzymes associated with diabetes and Alzheimer's disease by 1,3,4-oxadiazole derivatives: Synthesis, in vitro screening, and computational studies.
Arch Pharm (Weinheim)
; 356(12): e2300384, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37806747
10.
Effects of long-term Ailanthus altissima extract supplementation on fear, cognition and brain antioxidant levels.
Saudi Pharm J
; 31(2): 191-206, 2023 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-36942273
11.
Phytochemical characterization and anti-arthritic potential of Croton bonplandianus leaves extract: In-vivo and in-silico approach.
Saudi Pharm J
; 31(12): 101860, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38192284
12.
Levetiracetam ameliorates epileptogenesis by modulating the adenosinergic pathway in a kindling model of epilepsy in mice.
Turk J Med Sci
; 53(5): 1045-1057, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38813043
13.
Isatin thiazoles as antidiabetic: Synthesis, in vitro enzyme inhibitory activities, kinetics, and in silico studies.
Arch Pharm (Weinheim)
; 355(6): e2100481, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35355329
14.
Re-purposing of hepatitis C virus FDA approved direct acting antivirals as potential SARS-CoV-2 protease inhibitors.
J Mol Struct
; 1250: 131920, 2022 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34815586
15.
Identification of Selective BRD9 Inhibitor via Integrated Computational Approach.
Int J Mol Sci
; 23(21)2022 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36362300
16.
Cheminformatics-Based Discovery of Potential Chemical Probe Inhibitors of Omicron Spike Protein.
Int J Mol Sci
; 23(18)2022 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36142242
17.
Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies.
Int J Mol Sci
; 23(19)2022 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36233160
18.
Virtual Screening, Synthesis and Biological Evaluation of Streptococcus mutans Mediated Biofilm Inhibitors.
Molecules
; 27(4)2022 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35209243
19.
Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as ß-Glucuronidase Inhibitors: In Vitro and In Silico Studies.
Molecules
; 27(22)2022 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36431887
20.
Sarcorucinine-D Inhibits Cholinesterases and Calcium Channels: Molecular Dynamics Simulation and In Vitro Mechanistic Investigations.
Molecules
; 27(11)2022 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35684298