Detalles de la búsqueda
1.
Potent antiproliferative effects of 25-hydroxy-16-ene-23-yne-vitamin D3 that resists the catalytic activity of both CYP27B1 and CYP24A1.
J Cell Biochem
; 115(8): 1392-402, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24535953
2.
Novel Gemini vitamin D3 analogs: large structure/function analysis and ability to induce antimicrobial peptide.
Int J Cancer
; 134(1): 207-17, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23775785
3.
A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α,25-dihydroxyvitamin D3.
Arch Biochem Biophys
; 509(1): 33-43, 2011 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21338573
4.
Selective inhibition of cyclooxygenase-2 (COX-2) by 1alpha,25-dihydroxy-16-ene-23-yne-vitamin D3, a less calcemic vitamin D analog.
J Cell Biochem
; 104(5): 1832-42, 2008 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18348265
5.
Synergistic antileukemic activity of carnosic acid-rich rosemary extract and the 19-nor Gemini vitamin D analogue in a mouse model of systemic acute myeloid leukemia.
Oncology
; 75(3-4): 203-14, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18852491
6.
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells.
Clin Cancer Res
; 12(7 Pt 1): 2004-13, 2006 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16609009
7.
Metabolism of selective 20-epi-vitamin D3 analogs in rat osteosarcoma UMR-106 cells: Isolation and identification of four novel C-1 fatty acid esters of 1α,25-dihydroxy-16-ene-20-epi-vitamin D3.
Steroids
; 119: 18-30, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28089927
8.
C-20 cyclopropyl vitamin D3 analogs.
Curr Top Med Chem
; 6(12): 1289-96, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-16848742
9.
1alpha,25-(OH)(2)-D(3) and its synthetic analogue decrease tumor load in the Apc(min) Mouse.
Cancer Res
; 62(3): 741-6, 2002 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11830528
10.
Effect of cellular environment on the selective activation of the vitamin D receptor by 1alpha,25-dihydroxyvitamin D3 and its analog 1alpha-fluoro-16-ene-20-epi-23-ene-26,27-bishomo-25-hydroxyvitamin D3 (Ro-26-9228).
Mol Endocrinol
; 18(4): 874-87, 2004 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-14726489
11.
Calcitriol derivatives with two different side chains at C-20. II. Diastereoselective syntheses of the metabolically produced 24(R)-hydroxygemini.
J Med Chem
; 47(26): 6476-84, 2004 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-15588082
12.
Novel Gemini analogs of 1alpha,25-dihydroxyvitamin D(3) with enhanced transcriptional activity.
Biochem Pharmacol
; 67(7): 1327-36, 2004 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15013848
13.
Calcitriol derivatives with two different side chains at C-20. 24-hydroxy derivatives as metabolic products and molecular probes for VDR exploration.
J Steroid Biochem Mol Biol
; 89-90(1-5): 35-8, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15225743
14.
Targeting 1alpha,25-dihydroxyvitamin D3 antiproliferative insensitivity in breast cancer cells by co-treatment with histone deacetylation inhibitors.
J Steroid Biochem Mol Biol
; 89-90(1-5): 245-9, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15225779
15.
Characterization of five 19-nor-analogs of 1alpha,25(OH)2-Vitamin D3 with 20-cyclopropyl-modified side-chains: implications for ligand binding and calcemic properties.
J Steroid Biochem Mol Biol
; 89-90(1-5): 99-106, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15225754
16.
Antiproliferative signalling by 1,25(OH)2D3 in prostate and breast cancer is suppressed by a mechanism involving histone deacetylation.
Recent Results Cancer Res
; 164: 83-98, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-12899515
17.
Diastereotopic and deuterium effects in gemini.
J Med Chem
; 56(10): 3878-88, 2013 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-23566225
18.
Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097.
Medchemcomm
; 2(5): 424-429, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22180837
19.
Calcitriol derivatives with two different side chains at C-20. V. Potent inhibitors of mammary carcinogenesis and inducers of leukemia differentiation.
J Med Chem
; 52(17): 5505-19, 2009 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-19685888
20.
Calcitriol derivatives with two different side-chains at C-20. Part 4: further chain modifications that alter VDR-dependent monocytic differentiation potency in human leukemia cells.
Bioorg Med Chem
; 15(13): 4444-55, 2007 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17485214