Detalles de la búsqueda
1.
Absorption, metabolism and excretion of 14C-emvododstat following repeat daily oral dose administration in human volunteers using a combination of microtracer radioactivity and high radioactivity doses.
Drug Metab Dispos
; 2023 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37852795
2.
Mass Balance and Absorption, Distribution, Metabolism, and Excretion Properties of Balcinrenone following Oral Administration in Combination with Intravenous Microtracer in Healthy Subjects.
Drug Metab Dispos
; 51(8): 995-1004, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37407094
3.
Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.
Drug Metab Dispos
; 51(4): 451-463, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36639243
4.
Towards human ex vivo organ perfusion models to elucidate drug pharmacokinetics in health and disease.
Drug Metab Rev
; 52(3): 438-454, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32551945
5.
Enteral Acetaminophen Bioavailability in Pediatric Intensive Care Patients Determined With an Oral Microtracer and Pharmacokinetic Modeling to Optimize Dosing.
Crit Care Med
; 47(12): e975-e983, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31609773
6.
Dose-linearity of the pharmacokinetics of an intravenous [14 C]midazolam microdose in children.
Br J Clin Pharmacol
; 85(10): 2332-2340, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31269280
7.
Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.
Drug Metab Dispos
; 44(7): 1005-13, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27103634
8.
Observational infant exploratory [(14)C]-paracetamol pharmacokinetic microdose/therapeutic dose study with accelerator mass spectrometry bioanalysis.
Br J Clin Pharmacol
; 80(1): 157-67, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25619398
9.
Automated combustion accelerator mass spectrometry for the analysis of biomedical samples in the low attomole range.
Anal Chem
; 86(15): 7635-41, 2014 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25033319
10.
Effect of red wine consumption on biomarkers of oxidative stress.
Alcohol Alcohol
; 48(2): 153-9, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-22859618
11.
Novel Explanted Human Liver Model to Assess Hepatic Extraction, Biliary Excretion and Transporter Function.
Clin Pharmacol Ther
; 114(1): 137-147, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37042227
12.
Predicting blood:air partition coefficients using basic physicochemical properties.
Regul Toxicol Pharmacol
; 62(1): 23-8, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22178169
13.
Assessment of dermal absorption of aluminium from a representative antiperspirant formulation using a (26Al)Al microtracer approach: a follow-up study in humans.
Toxicol Res (Camb)
; 11(3): 511-519, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35782644
14.
Microdosing as a Potential Tool to Enhance Clinical Development of Novel Antibiotics: A Tissue and Plasma PK Feasibility Study with Ciprofloxacin.
Clin Pharmacokinet
; 61(5): 697-707, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34997559
15.
Quantification of azacitidine incorporation into human DNA/RNA by accelerator mass spectrometry as direct measure of target engagement.
J Pharm Biomed Anal
; 202: 114152, 2021 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34051483
16.
The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study.
Clin Pharmacol Ther
; 109(1): 140-149, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32403162
17.
Proof of Concept: First Pediatric [14 C]microtracer Study to Create Metabolite Profiles of Midazolam.
Clin Pharmacol Ther
; 108(5): 1003-1009, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32386327
18.
Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya.
Toxicol In Vitro
; 23(4): 617-21, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19232536
19.
Assessment of Dermal Absorption of Aluminum from a Representative Antiperspirant Formulation Using a 26 Al Microtracer Approach.
Clin Transl Sci
; 11(6): 573-581, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30052317
20.
Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants.
Eur J Pharm Sci
; 124: 217-227, 2018 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30171984