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1.
Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy.
Toxicol Appl Pharmacol
; 434: 115797, 2022 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34780725
2.
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter.
Toxicol Appl Pharmacol
; 434: 115823, 2022 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34896433
3.
Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters.
Arch Toxicol
; 96(12): 3265-3277, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35972551
4.
Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study.
Int J Mol Sci
; 23(22)2022 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36430819
5.
Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo.
Int J Mol Sci
; 22(21)2021 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34769363
6.
Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance.
Drug Metab Dispos
; 47(7): 699-709, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31068367
7.
Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes.
Mol Pharm
; 16(11): 4436-4450, 2019 11 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31633365
8.
ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia.
Biomed Pharmacother
; 150: 112962, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35462331
9.
Sonidegib potentiates the cancer cells' sensitivity to cytostatic agents by functional inhibition of ABCB1 and ABCG2 in vitro and ex vivo.
Biochem Pharmacol
; 199: 115009, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35314165
10.
Encorafenib Acts as a Dual-Activity Chemosensitizer through Its Inhibitory Effect on ABCC1 Transporter In Vitro and Ex Vivo.
Pharmaceutics
; 14(12)2022 Nov 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-36559089
11.
Roles of CYP3A4, CYP3A5 and CYP2C8 drug-metabolizing enzymes in cellular cytostatic resistance.
Chem Biol Interact
; 340: 109448, 2021 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33775687
12.
Entrectinib reverses cytostatic resistance through the inhibition of ABCB1 efflux transporter, but not the CYP3A4 drug-metabolizing enzyme.
Biochem Pharmacol
; 178: 114061, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32497550
13.
Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme.
Cancers (Basel)
; 12(4)2020 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32231067
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