Detalles de la búsqueda
1.
A first in man study to evaluate the safety, pharmacokinetics and pharmacodynamics of RP7214, a dihydroorotate dehydrogenase inhibitor in healthy subjects.
Br J Clin Pharmacol
; 89(3): 1127-1138, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36217901
2.
A first-in-human study to evaluate the safety, tolerability and pharmacokinetics of RP3128, an oral calcium release-activated calcium (CRAC) channel modulator in healthy volunteers.
J Clin Pharm Ther
; 46(3): 677-687, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33314326
3.
Umbralisib, a novel PI3Kδ and casein kinase-1ε inhibitor, in relapsed or refractory chronic lymphocytic leukaemia and lymphoma: an open-label, phase 1, dose-escalation, first-in-human study.
Lancet Oncol
; 19(4): 486-496, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29475723
4.
A First-in-human Study of Tenalisib (RP6530), a Dual PI3K δ/γ Inhibitor, in Patients With Relapsed/Refractory Hematologic Malignancies: Results From the European Study.
Clin Lymphoma Myeloma Leuk
; 20(2): 78-86, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31761713
5.
Phase I/Ib Study of Tenalisib (RP6530), a Dual PI3K δ/γ Inhibitor in Patients with Relapsed/Refractory T-Cell Lymphoma.
Cancers (Basel)
; 12(8)2020 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32824175
6.
Targeting Cancer Cells and Tumor Microenvironment in Preclinical and Clinical Models of Hodgkin Lymphoma Using the Dual PI3Kδ/γ Inhibitor RP6530.
Clin Cancer Res
; 25(3): 1098-1112, 2019 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30352904
7.
Phase I/II evaluation of RV1001, a novel PI3Kδ inhibitor, in spontaneous canine lymphoma.
PLoS One
; 13(4): e0195357, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29689086
8.
Simultaneous Quantification of Baricitinib and Methotrexate in Rat Plasma by LC-MS/MS: Application to a Pharmacokinetic Study.
Sci Pharm
; 84(2): 347-59, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27222609
9.
Pharmacodynamic evaluation of RP3128, a novel and potent CRAC channel inhibitor in guinea pig models of allergic asthma.
Eur J Pharmacol
; 772: 62-70, 2016 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26724844
10.
Design, Synthesis, and Identification of Silicon Incorporated Oxazolidinone Antibiotics with Improved Brain Exposure.
ACS Med Chem Lett
; 6(11): 1105-10, 2015 Nov 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-26617962
11.
Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.
J Mass Spectrom
; 47(12): 1612-9, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23280750
12.
Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation.
Sci Pharm
; 80(3): 633-46, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23008811
Resultados
1 -
12
de 12
1
Próxima >
>>