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1.
Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay.
Bioorg Med Chem
; 21(5): 1209-18, 2013 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23347804
2.
Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis.
Chem Biodivers
; 9(3): 536-56, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22422522
3.
Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues.
Bioorg Med Chem Lett
; 20(3): 844-7, 2010 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20064721
4.
Structure-based drug repositioning explains ibrutinib as VEGFR2 inhibitor.
PLoS One
; 15(5): e0233089, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32459810
5.
OSU-T315 as an Interesting Lead Molecule for Novel B Cell-Specific Therapeutics.
J Immunol Res
; 2018: 2505818, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30276218
6.
Comparative In Vitro Immune Stimulation Analysis of Primary Human B Cells and B Cell Lines.
J Immunol Res
; 2016: 5281823, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-28116319
7.
Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis.
J Med Chem
; 54(13): 4847-62, 2011 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21657202
8.
Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity.
J Med Chem
; 54(2): 655-68, 2011 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-21171614
9.
Beta-cell replication is increased in donor organs from young patients after prolonged life support.
Diabetes
; 59(7): 1702-8, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20413508
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