Detalles de la búsqueda
1.
Evaluation of Interindividual Human Variation in Bioactivation and DNA Adduct Formation of Estragole in Liver Predicted by Physiologically Based Kinetic/Dynamic and Monte Carlo Modeling.
Chem Res Toxicol
; 29(4): 659-68, 2016 Apr 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26952143
2.
Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations.
Toxicol Appl Pharmacol
; 283(2): 117-26, 2015 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25549870
3.
Effects of pre-exercise sucralose ingestion on carbohydrate oxidation during exercise.
Int J Sport Nutr Exerc Metab
; 23(6): 584-92, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23689036
4.
Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat.
Toxicol Appl Pharmacol
; 260(3): 271-84, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22445790
5.
In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling.
Mutagenesis
; 27(6): 653-63, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22844077
6.
Quantitative comparison between in vivo DNA adduct formation from exposure to selected DNA-reactive carcinogens, natural background levels of DNA adduct formation and tumour incidence in rodent bioassays.
Mutagenesis
; 26(5): 605-18, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21642616
7.
Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells.
Biopharm Drug Dispos
; 32(9): 530-5, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22083890
8.
Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.
Drug Metab Dispos
; 38(4): 617-25, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20056724
9.
A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes.
Toxicol Appl Pharmacol
; 245(1): 57-66, 2010 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20144636
10.
Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model.
Mol Syst Biol
; 4: 157, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18197175
11.
Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model.
Mol Syst Biol
; 4: 205, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18628745
12.
Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya.
Toxicol In Vitro
; 23(4): 617-21, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19232536
13.
A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model.
Mol Syst Biol
; 3: 112, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17515922
14.
Metabolism and transport of the citrus flavonoid hesperetin in Caco-2 cell monolayers.
Drug Metab Dispos
; 36(9): 1794-802, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18515333
15.
A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat.
Toxicol Appl Pharmacol
; 231(2): 248-59, 2008 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18539307
16.
Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2.
Environ Toxicol Pharmacol
; 26(1): 102-8, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21783896
17.
Functional peptides by genome reverse engineering.
Curr Opin Drug Discov Devel
; 10(3): 341-6, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17554861
18.
Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity.
Biochem Pharmacol
; 72(2): 217-26, 2006 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-16756964
19.
Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients.
Biomed Pharmacother
; 60(9): 508-19, 2006 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16978825
20.
Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids.
J Agric Food Chem
; 54(15): 5350-8, 2006 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-16848516