Detalles de la búsqueda
1.
Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5-week study in A/J mice.
J Appl Toxicol
; 42(10): 1701-1722, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35543240
2.
In Vivo Profiling of a Natural Alkaloid, Anatabine, in Rodents: Pharmacokinetics and Anti-Inflammatory Efficacy.
J Nat Prod
; 84(4): 1012-1021, 2021 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33706515
3.
A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Arch Toxicol
; 95(5): 1805-1829, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33963423
4.
Impact of whole-body versus nose-only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2-month cigarette smoke exposure study in the ApoE-/- mouse model.
J Appl Toxicol
; 41(10): 1598-1619, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33825214
5.
A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.
Am J Physiol Heart Circ Physiol
; 318(3): H604-H631, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31975625
6.
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague-Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.
Arch Toxicol
; 94(6): 2179-2206, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32367274
7.
Respirable aerosol exposures of nicotine dry powder formulations to in vitro, ex vivo, and in vivo pre-clinical models demonstrate consistency of pharmacokinetic profiles.
Inhal Toxicol
; 31(6): 248-257, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31496314
8.
Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.
Inhal Toxicol
; 30(13-14): 553-567, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30849254
9.
Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.
Inhal Toxicol
; 28(5): 226-40, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27027324
10.
Evaluation of the Tobacco Heating System 2.2. Part 1: Description of the system and the scientific assessment program.
Regul Toxicol Pharmacol
; 81 Suppl 2: S17-S26, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27450400
11.
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S59-S81, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27793746
12.
Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol.
Regul Toxicol Pharmacol
; 81 Suppl 2: S27-S47, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27720919
13.
Evaluation of the Tobacco Heating System 2.2. Part 7: Systems toxicological assessment of a mentholated version revealed reduced cellular and molecular exposure effects compared with mentholated and non-mentholated cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S123-S138, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27818347
14.
Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S93-S122, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27818348
15.
A framework for in vitro systems toxicology assessment of e-liquids.
Toxicol Mech Methods
; 26(6): 389-413, 2016 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-27117495
16.
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology.
Inhal Toxicol
; 27(9): 405-31, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26295358
17.
Deconvolution of Systemic Pharmacokinetics Predicts Inhaled Aerosol Dosimetry of Nicotine.
Eur J Pharm Sci
; 180: 106321, 2023 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36336278
18.
Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies.
J Vis Exp
; (182)2022 04 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35499356
19.
Toxicological Assessment of Flavor Ingredients in E-Vapor Products.
Front Toxicol
; 4: 878976, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35516526
20.
Impact of 6-Month Exposure to Aerosols From Potential Modified Risk Tobacco Products Relative to Cigarette Smoke on the Rodent Gastrointestinal Tract.
Front Microbiol
; 12: 587745, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34276574