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1.
Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies.
Eur J Nucl Med Mol Imaging
; 46(10): 2178-2189, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31264169
2.
Discovery and characterization of novel indole and 7-azaindole derivatives as inhibitors of ß-amyloid-42 aggregation for the treatment of Alzheimer's disease.
Bioorg Med Chem Lett
; 27(6): 1405-1411, 2017 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28216401
3.
Synthesis and structure-activity relationship of 2,6-disubstituted pyridine derivatives as inhibitors of ß-amyloid-42 aggregation.
Bioorg Med Chem Lett
; 26(14): 3330-3335, 2016 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27256911
4.
An effector-reduced anti-ß-amyloid (Aß) antibody with unique aß binding properties promotes neuroprotection and glial engulfment of Aß.
J Neurosci
; 32(28): 9677-89, 2012 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22787053
5.
Discovery and structure activity relationship of small molecule inhibitors of toxic ß-amyloid-42 fibril formation.
J Biol Chem
; 287(41): 34786-800, 2012 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-22891248
6.
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies.
Eur J Med Chem
; 204: 112615, 2020 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32771872
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