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1.
Cognitive Decline and BPSD Are Concomitant with Autophagic and Synaptic Deficits Associated with G9a Alterations in Aged SAMP8 Mice.
Cells
; 11(16)2022 08 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36010679
2.
Microarray Analysis Revealed Inflammatory Transcriptomic Changes after LSL60101 Treatment in 5XFAD Mice Model.
Genes (Basel)
; 12(9)2021 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34573297
3.
Disease-modifying treatment with I2 imidazoline receptor ligand LSL60101 in an Alzheimer's disease mouse model: a comparative study with donepezil.
Br J Pharmacol
; 178(15): 3017-3033, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33817786
4.
I2 imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway.
Geroscience
; 43(2): 965-983, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33128688
5.
Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer's disease.
Eur J Med Chem
; 222: 113540, 2021 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34118720
6.
Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I2-Imidazoline Receptor Ligand MCR5.
Pharmaceutics
; 12(5)2020 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32456135
7.
Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease.
J Med Chem
; 63(7): 3610-3633, 2020 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32150414
8.
Behavioral and Cognitive Improvement Induced by Novel Imidazoline I2 Receptor Ligands in Female SAMP8 Mice.
Neurotherapeutics
; 16(2): 416-431, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30460457
9.
11ß-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model.
Mol Neurobiol
; 55(12): 8904-8915, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29611102
10.
Correction to Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease.
J Med Chem
; 63(18): 10529, 2020 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32924503
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