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1.
Integrated laser ablation-dropletProbe-mass spectrometry for absolute drug quantitation, metabolite detection, and distribution in tissue.
Rapid Commun Mass Spectrom
; 35(23): e9202, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34545636
2.
Absolute quantitation of propranolol from 200-µm regions of mouse brain and liver thin tissues using laser ablation-dropletProbe-mass spectrometry.
Rapid Commun Mass Spectrom
; 35(5): e9010, 2021 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33232548
3.
Autonomic Dysfunction Linked to Inhibition of the Nav1.7 Sodium Channel.
Circulation
; 149(17): 1394-1396, 2024 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38648272
4.
Online, Absolute Quantitation of Propranolol from Spatially Distinct 20- and 40-µm Dissections of Brain, Liver, and Kidney Thin Tissue Sections by Laser Microdissection-Liquid Vortex Capture-Mass Spectrometry.
Anal Chem
; 88(11): 6026-34, 2016 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27214103
5.
Extraction efficiency and implications for absolute quantitation of propranolol in mouse brain, liver and kidney tissue sections using droplet-based liquid microjunction surface sampling high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Rapid Commun Mass Spectrom
; 30(14): 1705-1712, 2016 07 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-28328034
6.
From molecules to visuals: Empowering drug discovery and development with mass spectrometry imaging.
J Mass Spectrom
; 59(5): e5029, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38656528
7.
Development and Application of DropletProbe Mass Spectrometry for Examining Biodistribution of Therapeutics.
Methods Mol Biol
; 2437: 171-180, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-34902148
8.
Mass spectrometry imaging of diclofenac and its metabolites in tissues using nanospray desorption electrospray ionization.
Anal Chim Acta
; 1233: 340490, 2022 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36283780
9.
Guiding Chemically Synthesized Peptide Drug Lead Optimization by Derisking Mast Cell Degranulation-Related Toxicities of a NaV1.7 Peptide Inhibitor.
Toxicol Sci
; 185(2): 170-183, 2022 01 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34897513
10.
The Invention of WM382, a Highly Potent PMIX/X Dual Inhibitor toward the Treatment of Malaria.
ACS Med Chem Lett
; 13(11): 1745-1754, 2022 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36385924
11.
Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain.
J Med Chem
; 65(1): 485-496, 2022 01 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34931831
12.
Antiviral efficacy upon administration of a HepDirect prodrug of 2'-C-methylcytidine to hepatitis C virus-infected chimpanzees.
Antimicrob Agents Chemother
; 55(8): 3854-60, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21628542
13.
Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example.
Rapid Commun Mass Spectrom
; 25(23): 3587-96, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22095508
14.
Simultaneous multielement imaging of liver tissue using laser ablation inductively coupled plasma mass spectrometry.
Talanta
; 235: 122725, 2021 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34517593
15.
Optimization of dropletProbe-Mass Spectrometry for Whole-Body Tissue Distribution Analysis of Drug-Like Molecules.
J Am Soc Mass Spectrom
; 31(12): 2558-2562, 2020 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32538626
16.
Combining MALDI mass spectrometry imaging and droplet-base surface sampling analysis for tissue distribution, metabolite profiling, and relative quantification of cyclic peptide melanotan II.
Anal Chim Acta
; 1125: 279-287, 2020 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32674774
17.
Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle.
Cell Host Microbe
; 27(4): 642-658.e12, 2020 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32109369
18.
Comparison of drug distribution images from whole-body thin tissue sections obtained using desorption electrospray ionization tandem mass spectrometry and autoradiography.
Anal Chem
; 80(13): 5168-77, 2008 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18481874
19.
Liquid microjunction surface sampling probe electrospray mass spectrometry for detection of drugs and metabolites in thin tissue sections.
J Mass Spectrom
; 43(4): 500-8, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18035855
20.
Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates.
J Control Release
; 183: 124-37, 2014 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24657948
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