Detalles de la búsqueda
1.
A structure-activity relationship study of Forkhead Domain Inhibitors (FDI): The importance of halogen binding interactions.
Bioorg Chem
; 93: 103269, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31654840
2.
Identification and Characterization of Novel Receptor-Interacting Serine/Threonine-Protein Kinase 2 Inhibitors Using Structural Similarity Analysis.
J Pharmacol Exp Ther
; 365(2): 354-367, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29555876
3.
Anti-inflammatory and antioxidant properties of a novel resveratrol-salicylate hybrid analog.
Bioorg Med Chem Lett
; 26(5): 1411-5, 2016 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26850006
4.
Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents.
J Enzyme Inhib Med Chem
; 31(5): 695-703, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26118420
5.
NSAIDs do not require the presence of a carboxylic acid to exert their anti-inflammatory effect - why do we keep using it?
J Enzyme Inhib Med Chem
; 31(6): 1018-28, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26403939
6.
3,4',5-trans-Trimethoxystilbene; a natural analogue of resveratrol with enhanced anticancer potency.
Invest New Drugs
; 33(3): 775-86, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25720605
7.
Design and synthesis of resveratrol-salicylate hybrid derivatives as CYP1A1 inhibitors.
J Enzyme Inhib Med Chem
; 30(6): 884-95, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25407017
8.
Medicinal chemistry curriculum and pedagogical practices at Canadian pharmacy schools: Towards standardization of practice.
Curr Pharm Teach Learn
; : 102095, 2024 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38755059
9.
Positional isomers of aspirin are equally potent in inhibiting colon cancer cell growth: differences in mode of cyclooxygenase inhibition.
J Pharmacol Exp Ther
; 345(1): 85-94, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23349335
10.
Comparison of phenelzine and geometric isomers of its active metabolite, ß-phenylethylidenehydrazine, on rat brain levels of amino acids, biogenic amine neurotransmitters and methylamine.
J Neural Transm (Vienna)
; 120(6): 987-96, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23392617
11.
The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase.
Diabetes
; 72(1): 126-134, 2023 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36256885
12.
Effects of nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NONO-NSAIDs) on melanoma cell adhesion.
Toxicol Appl Pharmacol
; 264(2): 161-6, 2012 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22889880
13.
Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
Bioorg Med Chem
; 20(9): 2912-22, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22475926
14.
Structure-Activity Relationship of N-Phenylthieno[2,3-b]pyridine-2-carboxamide Derivatives Designed as Forkhead Box M1 Inhibitors: The Effect of Electron-Withdrawing and Donating Substituents on the Phenyl Ring.
Pharmaceuticals (Basel)
; 15(3)2022 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35337081
15.
Targeting of the FOXM1 Oncoprotein by E3 Ligase-Assisted Degradation.
J Med Chem
; 64(23): 17098-17114, 2021 12 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34812040
16.
FOXM1 Inhibitors as Potential Diagnostic Agents: First Generation of a PET Probe Targeting FOXM1 To Detect Triple-Negative Breast Cancer inâ vitro and inâ vivo.
ChemMedChem
; 16(24): 3720-3729, 2021 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-34402202
17.
SP1-independent inhibition of FOXM1 by modified thiazolidinediones.
Eur J Med Chem
; 209: 112902, 2021 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33069434
18.
Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.
Cell Metab
; 31(5): 909-919.e8, 2020 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32275862
19.
Myeloperoxidase-mediated oxidation of edaravone produces an apparent non-toxic free radical metabolite and modulates hydrogen peroxide-mediated cytotoxicity in HL-60â¯cells.
Free Radic Biol Med
; 143: 422-432, 2019 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31445206
20.
Untying the knot of transcription factor druggability: Molecular modeling study of FOXM1 inhibitors.
J Mol Graph Model
; 80: 197-210, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29414039