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1.
A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function.
Mol Cell
; 33(1): 43-52, 2009 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19150426
2.
A crosstalk between hepcidin and IRE/IRP pathways controls ferroportin expression and determines serum iron levels in mice.
Elife
; 112022 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36066082
3.
Clinical stage EGFR inhibitors irreversibly alkylate Bmx kinase.
Bioorg Med Chem Lett
; 18(22): 5916-9, 2008 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18667312
4.
DAPK catalytic activity in the hippocampus increases during the recovery phase in an animal model of brain hypoxic-ischemic injury.
Biochim Biophys Acta
; 1600(1-2): 128-37, 2002 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-12445468
5.
Structure, activity, regulation, and inhibitor discovery for a protein kinase associated with apoptosis and neuronal death.
Pharmacol Ther
; 93(2-3): 217-24, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12191613
6.
Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic antineuroinflammatory compound.
J Med Chem
; 45(3): 563-6, 2002 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-11806708
7.
Discovery of a new class of synthetic protein kinase inhibitors that suppress selective aspects of glial activation and protect against beta-amyloid induced injury: a foundation for future medicinal chemistry efforts focused on targeting Alzheimer's disease progression.
J Mol Neurosci
; 20(3): 411-23, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14501026
8.
MLCK210 gene knockout or kinase inhibition preserves lung function following endotoxin-induced lung injury in mice.
Am J Physiol Lung Cell Mol Physiol
; 292(6): L1327-34, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17307813
9.
Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesis.
Biochemistry
; 45(45): 13614-21, 2006 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-17087515
10.
Allosteric inhibitors of Bcr-abl-dependent cell proliferation.
Nat Chem Biol
; 2(2): 95-102, 2006 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16415863
11.
Death-associated protein kinase as a potential therapeutic target.
Expert Opin Ther Targets
; 6(4): 497-506, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12223064
12.
A calmodulin-regulated protein kinase linked to neuron survival is a substrate for the calmodulin-regulated death-associated protein kinase.
Biochemistry
; 43(25): 8116-24, 2004 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-15209507
13.
An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury.
Bioorg Med Chem Lett
; 13(20): 3465-70, 2003 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-14505650
14.
Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment.
Proc Natl Acad Sci U S A
; 100(10): 6233-8, 2003 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-12730364
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