Búsqueda | Biblioteca Virtual en Salud

1.

Primary Neurons and Differentiated NSC-34 Cells Are More Susceptible to Arginine-Rich ALS Dipeptide Repeat Protein-Associated Toxicity than Non-Differentiated NSC-34 and CHO Cells.

Gill, Anna L; Wang, Monica Z; Levine, Beth; Premasiri, Alan; Vieira, Fernando G.

Int J Mol Sci ; 20(24)2019 Dec 11.

Artículo en Inglés | MEDLINE | ID: mdl-31835664

2.

PERK modulation, with GSK2606414, Sephin1 or salubrinal, failed to produce therapeutic benefits in the SOD1G93A mouse model of ALS.

Vieira, Fernando G; Tassinari, Valerie R; Kidd, Joshua D; Moreno, Andrew; Thompson, Kenneth; Perrin, Steven; Gill, Alan; Hatzipetros, Theo.

PLoS One ; 19(2): e0292190, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38359044

3.

Reduced C9orf72 expression exacerbates polyGR toxicity in patient iPSC-derived motor neurons and a Type I protein arginine methyltransferase inhibitor reduces that toxicity.

Dane, Therese L; Gill, Anna L; Vieira, Fernando G; Denton, Kyle R.

Front Cell Neurosci ; 17: 1134090, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37138766

4.

A machine-learning based objective measure for ALS disease severity.

Vieira, Fernando G; Venugopalan, Subhashini; Premasiri, Alan S; McNally, Maeve; Jansen, Aren; McCloskey, Kevin; Brenner, Michael P; Perrin, Steven.

NPJ Digit Med ; 5(1): 45, 2022 Apr 08.

Artículo en Inglés | MEDLINE | ID: mdl-35396385

5.

Hypothesis and Theory: Roles of Arginine Methylation in C9orf72-Mediated ALS and FTD.

Gill, Anna L; Premasiri, Alan S; Vieira, Fernando G.

Front Cell Neurosci ; 15: 633668, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-33833668

6.

Type I PRMT Inhibition Protects Against C9ORF72 Arginine-Rich Dipeptide Repeat Toxicity.

Premasiri, Alan S; Gill, Anna L; Vieira, Fernando G.

Front Pharmacol ; 11: 569661, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-33013410

7.

A High-throughput qPCR-based Method to Genotype the SOD1^G93A Mouse Model for Relative Copy Number.

Tassinari, Valerie R; Vieira, Fernando G.

Bio Protoc ; 9(12): e3276, 2019 Jun 20.

Artículo en Inglés | MEDLINE | ID: mdl-33654793

8.

SOD1-positive aggregate accumulation in the CNS predicts slower disease progression and increased longevity in a mutant SOD1 mouse model of ALS.

Gill, Cindy; Phelan, James P; Hatzipetros, Theo; Kidd, Joshua D; Tassinari, Valerie R; Levine, Beth; Wang, Monica Z; Moreno, Andrew; Thompson, Kenneth; Maier, Marcel; Grimm, Jan; Gill, Alan; Vieira, Fernando G.

Sci Rep ; 9(1): 6724, 2019 04 30.

Artículo en Inglés | MEDLINE | ID: mdl-31040321

9.

Design, power, and interpretation of studies in the standard murine model of ALS.

Scott, Sean; Kranz, Janice E; Cole, Jeff; Lincecum, John M; Thompson, Kenneth; Kelly, Nancy; Bostrom, Alan; Theodoss, Jill; Al-Nakhala, Bashar M; Vieira, Fernando G; Ramasubbu, Jeyanthi; Heywood, James A.

Amyotroph Lateral Scler ; 9(1): 4-15, 2008.

Artículo en Inglés | MEDLINE | ID: mdl-18273714

10.

A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis.

Maier, Marcel; Welt, Tobias; Wirth, Fabian; Montrasio, Fabio; Preisig, Daniel; McAfoose, Jordan; Vieira, Fernando G; Kulic, Luka; Späni, Claudia; Stehle, Thilo; Perrin, Steve; Weber, Markus; Hock, Christoph; Nitsch, Roger M; Grimm, Jan.

Sci Transl Med ; 10(470)2018 12 05.

Artículo en Inglés | MEDLINE | ID: mdl-30518612

11.

CuATSM efficacy is independently replicated in a SOD1 mouse model of ALS while unmetallated ATSM therapy fails to reveal benefits.

Vieira, Fernando G; Hatzipetros, Theo; Thompson, Kenneth; Moreno, Andy J; Kidd, Joshua D; Tassinari, Valerie R; Levine, Beth; Perrin, Steven; Gill, Alan.

IBRO Rep ; 2: 47-53, 2017 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-30135932

12.

A Quick Phenotypic Neurological Scoring System for Evaluating Disease Progression in the SOD1-G93A Mouse Model of ALS.

Hatzipetros, Theo; Kidd, Joshua D; Moreno, Andy J; Thompson, Kenneth; Gill, Alan; Vieira, Fernando G.

J Vis Exp ; (104)2015 Oct 06.

Artículo en Inglés | MEDLINE | ID: mdl-26485052

13.

Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.

Vieira, Fernando G; Ping, Qinggong; Moreno, Andy J; Kidd, Joshua D; Thompson, Kenneth; Jiang, Bingbing; Lincecum, John M; Wang, Monica Z; De Zutter, Gerard S; Tassinari, Valerie R; Levine, Beth; Hatzipetros, Theo; Gill, Alan; Perrin, Steven.

PLoS One ; 10(8): e0135570, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26288094

14.

Impact of IL-1beta on flow-induced outward arterial remodeling.

Jiang, Zhihua; Berceli, Scott A; Pfahnl, Chun L; Wu, Lizhen; Killingsworth, Chris D; Vieira, Fernando G; Ozaki, C Keith.

Surgery ; 136(2): 478-82, 2004 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-15300218

15.

Dexpramipexole is ineffective in two models of ALS related neurodegeneration.

Vieira, Fernando G; LaDow, Eva; Moreno, Andy; Kidd, Joshua D; Levine, Beth; Thompson, Kenneth; Gill, Alan; Finkbeiner, Steven; Perrin, Steven.

PLoS One ; 9(12): e91608, 2014.

Artículo en Inglés | MEDLINE | ID: mdl-25526593

16.

C57BL/6J congenic Prp-TDP43A315T mice develop progressive neurodegeneration in the myenteric plexus of the colon without exhibiting key features of ALS.

Hatzipetros, Theo; Bogdanik, Laurent P; Tassinari, Valerie R; Kidd, Joshua D; Moreno, Andy J; Davis, Crystal; Osborne, Melissa; Austin, Andrew; Vieira, Fernando G; Lutz, Cathleen; Perrin, Steve.

Brain Res ; 1584: 59-72, 2014 Oct 10.

Artículo en Inglés | MEDLINE | ID: mdl-24141148

17.

From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis.

Lincecum, John M; Vieira, Fernando G; Wang, Monica Z; Thompson, Kenneth; De Zutter, Gerald S; Kidd, Joshua; Moreno, Andrew; Sanchez, Ricardo; Carrion, Isarelis J; Levine, Beth A; Al-Nakhala, Bashar M; Sullivan, Shawn M; Gill, Alan; Perrin, Steven.

Nat Genet ; 42(5): 392-9, 2010 May.

Artículo en Inglés | MEDLINE | ID: mdl-20348957

18.

Complement component C6 innhibition decreases neurological disability in female transgenic SOD1 G93A mouse model of amyotrophic lateral sclerosis

Idrissi, Nawal Bahia El; Fluiter, Kees; Vieira, Fernando G; Baas, Frank.

In. Idrissi, Nawal Bahia El. Complement in neuroinflammation: studies in leprosy and amyotrophic lateral sclerosis. Amsterdam, Ridderprint B. V, 2017. p.211-237, tab, graf.

Monografía en Inglés | SES-SP, SESSP-ILSLACERVO, SES-SP | ID: biblio-1084195

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