Detalles de la búsqueda
1.
A randomized, double-blind, placebo-controlled, single and multiple ascending dose Phase 1 study to determine the safety, pharmacokinetics and food and faecal microbiome effects of ibezapolstat administered orally to healthy subjects.
J Antimicrob Chemother
; 75(12): 3635-3643, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32892222
2.
Interaction of Ethanol and Oral ANS-6637, a Selective ALDH2 Inhibitor in Males: A Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Cohort Study.
Alcohol Clin Exp Res
; 44(9): 1885-1895, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32687612
3.
Pharmacokinetics and Abuse Potential of Asalhydromorphone, a Novel Prodrug of Hydromorphone, After Intranasal Administration in Recreational Drug Users.
Pain Med
; 21(3): 511-520, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30986302
4.
Human Abuse Potential of Oral NKTR-181 in Recreational Opioid Users: A Randomized, Double-Blind, Crossover Study.
Pain Med
; 21(2): e114-e126, 2020 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31553457
5.
A randomized, double-blind, placebo-controlled study of the kappa opioid receptor antagonist, CERC-501, in a human laboratory model of smoking behavior.
Addict Biol
; 25(4): e12799, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31240842
6.
Sustained-Release Buprenorphine (RBP-6000) Blocks the Effects of Opioid Challenge With Hydromorphone in Subjects With Opioid Use Disorder.
J Clin Psychopharmacol
; 36(1): 18-26, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26650971
7.
Effect of steady-state faldaprevir on the pharmacokinetics of steady-state methadone and buprenorphine-naloxone in subjects receiving stable addiction management therapy.
Antimicrob Agents Chemother
; 59(1): 498-504, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25385094
8.
A randomized, double-blind, multiple-dose study of the pan-genotypic NS5A inhibitor samatasvir in patients infected with hepatitis C virus genotype 1, 2, 3 or 4.
J Hepatol
; 60(5): 920-7, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24434503
9.
A phase 1 study investigating DX-2930 in healthy subjects.
Ann Allergy Asthma Immunol
; 113(4): 460-6.e2, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24980392
10.
Oral, intranasal, and intravenous abuse potential of serdexmethylphenidate, a novel prodrug of d-methylphenidate.
Curr Med Res Opin
; 38(7): 1237-1250, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35570699
11.
A phase I study of the effect of repeated oral doses of pantoprazole on the pharmacokinetics of a single dose of fedratinib in healthy male subjects.
Cancer Chemother Pharmacol
; 85(5): 995-1001, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32318809
12.
Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations.
Drugs R D
; 20(1): 23-37, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-32130679
13.
Polyvalent Human Immune Globulin: A Prospective, Open-Label Study Assessing Anti-Hepatitis A Virus (HAV) Antibody Levels, Pharmacokinetics, and Safety in HAV-Seronegative Healthy Subjects.
Adv Ther
; 37(5): 2373-2389, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32301062
14.
Abuse Potential of Buprenorphine/Samidorphan Combination Compared to Buprenorphine and Placebo: A Phase 1 Randomized Controlled Trial.
J Clin Pharmacol
; 59(2): 206-217, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30102427
15.
Abuse potential of mirogabalin in recreational polydrug users.
Ther Adv Drug Saf
; 10: 2042098619836032, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31057786
16.
Abuse Potential of Samidorphan: A Phase I, Oxycodone-, Pentazocine-, Naltrexone-, and Placebo-Controlled Study.
J Clin Pharmacol
; 59(2): 218-228, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30476361
17.
A randomized, double-blind, placebo-controlled, crossover study to evaluate the human abuse liability of solriamfetol, a selective dopamine and norepinephrine reuptake inhibitor.
J Psychopharmacol
; 32(12): 1351-1361, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30269642
18.
The Pharmacodynamics, Pharmacokinetics, and Safety of Arhalofenate in Combination with Febuxostat When Treating Hyperuricemia Associated with Gout.
J Rheumatol
; 44(3): 374-379, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27980008
19.
Effect of Buprenorphine Weekly Depot (CAM2038) and Hydromorphone Blockade in Individuals With Opioid Use Disorder: A Randomized Clinical Trial.
JAMA Psychiatry
; 74(9): 894-902, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28655025
20.
Pharmacokinetics and pharmacodynamics of guanfacine extended release in adolescents aged 13-17 years with attention-deficit/hyperactivity disorder.
Clin Pharmacol Drug Dev
; 3(4): 252-61, 2014 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27128830