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1.
Increasing Enzyme Mannose-6-Phosphate Levels but Not Miglustat Coadministration Enhances the Efficacy of Enzyme Replacement Therapy in Pompe Mice.
J Pharmacol Exp Ther
; 387(2): 188-203, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37679046
2.
First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G-protein-biased sphingosine-1 phosphate receptor-1 agonist for endothelial protection.
Br J Clin Pharmacol
; 87(2): 598-611, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32520410
3.
Endothelial-protective effects of a G-protein-biased sphingosine-1 phosphate receptor-1 agonist, SAR247799, in type-2 diabetes rats and a randomized placebo-controlled patient trial.
Br J Clin Pharmacol
; 87(5): 2303-2320, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33125753
4.
Absorption, Metabolism, and Excretion of [14C]-Tolebrutinib After Oral Administration in Humans, Contribution of the Metabolites to Pharmacological Activity.
Clin Drug Investig
; 43(8): 653-665, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37642857
5.
Long-term Safety and Efficacy of Avalglucosidase Alfa in Patients With Late-Onset Pompe Disease.
Neurology
; 2022 May 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35618441
6.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study.
Am J Cardiovasc Drugs
; 20(5): 489-503, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32080823
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