Detalles de la búsqueda
1.
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague-Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.
Arch Toxicol
; 94(6): 2179-2206, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32367274
2.
Quantifying the risk-reduction potential of new Modified Risk Tobacco Products.
Regul Toxicol Pharmacol
; 92: 358-369, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-29258927
3.
Multicomponent aerosol particle deposition in a realistic cast of the human upper respiratory tract.
Inhal Toxicol
; 29(3): 113-125, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28470142
4.
Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.
Inhal Toxicol
; 28(5): 226-40, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27027324
5.
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S59-S81, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27793746
6.
Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke.
Regul Toxicol Pharmacol
; 81 Suppl 2: S93-S122, 2016 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27818348
7.
Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD).
Int J Mol Sci
; 17(9)2016 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-27657052
8.
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology.
Inhal Toxicol
; 27(9): 405-31, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26295358
9.
Cigarette smoke and LDL cooperate in reducing nitric oxide bioavailability in endothelial cells via effects on both eNOS and NADPH oxidase.
Nitric Oxide
; 27(3): 176-84, 2012 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22766265
10.
Effectiveness of strategies to increase the validity of findings from association studies: size vs. replication.
BMC Med Res Methodol
; 10: 47, 2010 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20509879
11.
Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke.
Toxicol Sci
; 178(1): 44-70, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32780830
12.
Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case.
Toxicol Rep
; 7: 1187-1206, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32995294
13.
Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.
Toxicol Sci
; 178(1): 138-158, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32780831
14.
Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke.
Comput Struct Biotechnol J
; 18: 1056-1073, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32419906
15.
A six-month systems toxicology inhalation/cessation study in ApoE-/- mice to investigate cardiovascular and respiratory exposure effects of modified risk tobacco products, CHTP 1.2 and THS 2.2, compared with conventional cigarettes.
Food Chem Toxicol
; 126: 113-141, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30763686
16.
Delivery efficiencies of constituents of combustion-derived aerosols across the air-liquid interface during in vitro exposures.
Toxicol In Vitro
; 52: 384-398, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30003980
17.
Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.
Food Chem Toxicol
; 115: 109-126, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29501877
18.
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.
Food Chem Toxicol
; 116(Pt B): 388-413, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29654848
19.
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. II. Systems toxicology assessment.
Food Chem Toxicol
; 115: 284-301, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29545142
20.
Assessment of the impact of aerosol from a potential modified risk tobacco product compared with cigarette smoke on human organotypic oral epithelial cultures under different exposure regimens.
Food Chem Toxicol
; 115: 148-169, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29505817