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1.
Model-Based Exposure-Response Assessment for Spectinamide 1810 in a Mouse Model of Tuberculosis.
Antimicrob Agents Chemother
; 65(11): e0174420, 2021 10 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34424046
2.
Bioavailability testing of a newly developed clindamycin oral suspension in a pediatric porcine model.
Pharm Dev Technol
; 24(8): 1038-1043, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-31134840
3.
Electrophilicity of pyridazine-3-carbonitrile, pyrimidine-2-carbonitrile, and pyridine-carbonitrile derivatives: a chemical model to describe the formation of thiazoline derivatives in human liver microsomes.
Chem Res Toxicol
; 27(12): 2052-61, 2014 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25372409
4.
Practical and economical implementation of online H/D exchange in LC-MS.
Anal Chem
; 85(22): 10904-12, 2013 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24117319
5.
Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics.
Pharmaceutics
; 15(6)2023 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37376207
6.
Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.
J Med Chem
; 65(6): 4534-4564, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35261239
7.
Discovery of (S)-1-((2',6-Bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain.
J Med Chem
; 65(6): 4457-4480, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35257579
8.
Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis.
ACS Infect Dis
; 7(10): 2850-2863, 2021 10 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34546724
9.
Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence.
ACS Appl Mater Interfaces
; 11(42): 38537-38554, 2019 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31553876
10.
Tannic acid-inspired paclitaxel nanoparticles for enhanced anticancer effects in breast cancer cells.
J Colloid Interface Sci
; 535: 133-148, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30292104
11.
Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice.
Tuberculosis (Edinb)
; 114: 119-122, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30711150
12.
Relative quantitation of endogenous proteins by quadrupole-time of flight and tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1106-1107: 11-18, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30615973
13.
Reverse Translation of US Food and Drug Administration Reviews of Oncology New Molecular Entities Approved in 2011-2017: Lessons Learned for Anticancer Drug Development.
Clin Transl Sci
; 11(2): 123-146, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29266809
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