Detalles de la búsqueda
1.
Rational design and synthesis of 2,4-dichloro-6-methyl pyrimidine derivatives as potential selective EGFRT790M/L858R inhibitors for the treatment of non-small cell lung cancer.
Arch Pharm (Weinheim)
; 357(5): e2300736, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38381049
2.
Discovery of novel 4-arylamino-quinazoline derivatives as EGFRL858R/T790M inhibitors with the potential to inhibit the non-small cell lung cancers.
Bioorg Chem
; 127: 105994, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35792314
3.
Design, synthesis and biological evaluation of novel 4-anlinoquinazoline derivatives as EGFR inhibitors with the potential to inhibit the gefitinib-resistant nonsmall cell lung cancers.
J Enzyme Inhib Med Chem
; 34(1): 203-217, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30835140
4.
Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors.
Molecules
; 24(19)2019 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31547116
5.
Discovery of novel 2-substituted-4-phenoxypyridine derivatives as potential antitumor agents.
Bioorg Med Chem Lett
; 28(3): 254-259, 2018 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29317165
6.
Design, Synthesis and Biological Evaluation of Novel Phenylsulfonylurea Derivatives as PI3K/mTOR Dual Inhibitors.
Molecules
; 23(7)2018 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29954109
7.
Design, synthesis and antitumor activity of Novel Sorafenib derivatives bearing pyrazole scaffold.
Bioorg Med Chem
; 25(20): 5754-5763, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28927801
8.
Design, synthesis, and docking studies of quinazoline analogues bearing aryl semicarbazone scaffolds as potent EGFR inhibitors.
Bioorg Med Chem
; 25(12): 3148-3157, 2017 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28428040
9.
Synthesis, activity and docking studies of phenylpyrimidine-carboxamide Sorafenib derivatives.
Bioorg Med Chem
; 24(23): 6166-6173, 2016 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28340913
10.
Synthesis and Biological Evaluation of Novel 4-Morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine Derivatives Bearing Phenylpyridine/ Phenylpyrimidine-Carboxamides.
Molecules
; 21(11)2016 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-27809261
11.
Efficacy of WWQ-131, a highly selective JAK2 inhibitor, in mouse models of myeloproliferative neoplasms.
Biomed Pharmacother
; 156: 113884, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36306591
12.
Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors.
Eur J Med Chem
; 244: 114856, 2022 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36279692
13.
Discovery of novel quinazoline derivatives bearing semicarbazone moiety as potent EGFR kinase inhibitors.
Comput Struct Biotechnol J
; 16: 462-478, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30455856
14.
Synthesis and bioevaluation and doking study of 1H-pyrrolo[2,3-b]pyridine derivatives bearing aromatic hydrazone moiety as c-Met inhibitors.
Eur J Med Chem
; 145: 315-327, 2018 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29331754
15.
Discovery of novel pyrrolopyrimidine/pyrazolopyrimidine derivatives bearing 1,2,3-triazole moiety as c-Met kinase inhibitors.
Chem Biol Drug Des
; 92(1): 1301-1314, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29575727
16.
Synthesis and antiproliferative activity of pyrrolo[2,3-b]pyridine derivatives bearing the 1,8-naphthyridin-2-one moiety.
Eur J Med Chem
; 143: 266-275, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29197731
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