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1.
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors.
Bioorg Chem
; 98: 103689, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32171993
2.
Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors.
J Med Chem
; 63(4): 1642-1659, 2020 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31961685
3.
Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer.
J Med Chem
; 62(22): 10108-10123, 2019 11 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31560541
4.
Development of Stem-Cell-Mobilizing Agents Targeting CXCR4 Receptor for Peripheral Blood Stem Cell Transplantation and Beyond.
J Med Chem
; 61(3): 818-833, 2018 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29314840
5.
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation.
Oncotarget
; 7(52): 86239-86256, 2016 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27863392
6.
Correction to Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors.
J Med Chem
; 63(13): 7445, 2020 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32573230
7.
Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: the role of the DFG motif in the design of epidermal growth factor receptor inhibitors.
J Med Chem
; 56(10): 3889-903, 2013 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-23611691
8.
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.
J Med Chem
; 53(20): 7316-26, 2010 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20961149
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