Detalles de la búsqueda
1.
Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2' amide-derivatives: Synthesis, biological evaluation and structural studies.
Bioorg Med Chem Lett
; 83: 129168, 2023 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36738797
2.
Structural studies of antiviral inhibitor with HIV-1 protease bearing drug resistant substitutions of V32I, I47V and V82I.
Biochem Biophys Res Commun
; 514(3): 974-978, 2019 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31092330
3.
Crystal structure of yeast nitronate monooxygenase from Cyberlindnera saturnus.
Proteins
; 86(5): 599-605, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29383742
4.
[Effects of Tongbi capsule on joint lesions in rabbits with rheumatoid arthritis].
Zhongguo Zhong Yao Za Zhi
; 43(5): 1034-1041, 2018 Mar.
Artículo
en Zh
| MEDLINE | ID: mdl-29676105
5.
Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1'-P2' ligands.
Bioorg Med Chem Lett
; 27(21): 4925-4931, 2017 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28958624
6.
Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex.
Bioorg Med Chem
; 25(19): 5114-5127, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28434781
7.
Paraventricular nucleus is involved in the central pathway of adipose afferent reflex in rats.
Can J Physiol Pharmacol
; 94(5): 534-41, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26963333
8.
Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands.
Bioorg Med Chem Lett
; 25(21): 4903-4909, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26096678
9.
Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands.
Org Biomol Chem
; 13(48): 11607-21, 2015 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26462551
10.
[Pathogen Characteristics of Catheter-related Bloodstream Infection].
Sichuan Da Xue Xue Bao Yi Xue Ban
; 46(5): 794-7, 2015 Sep.
Artículo
en Zh
| MEDLINE | ID: mdl-26619558
11.
Structure of choline oxidase in complex with the reaction product glycine betaine.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 2): 405-13, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24531474
12.
[Experimental study on anti-pancreatic cancer effect of oridonin].
Zhong Yao Cai
; 37(7): 1230-3, 2014 Jul.
Artículo
en Zh
| MEDLINE | ID: mdl-25566662
13.
[Anthraquinones and triterpenoids from roots of Knoxia roxburghii].
Zhongguo Zhong Yao Za Zhi
; 39(21): 4230-3, 2014 Nov.
Artículo
en Zh
| MEDLINE | ID: mdl-25775799
14.
Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 12): 2309-19, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24311573
15.
[Effect of panax notoginseng powder on pathological features and expressions of VEGF and its receptors of chronic subdural hematoma rabbits: an experimental study].
Zhongguo Zhong Xi Yi Jie He Za Zhi
; 33(7): 938-43, 2013 Jul.
Artículo
en Zh
| MEDLINE | ID: mdl-24063217
16.
Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation.
Eur J Med Chem
; 255: 115385, 2023 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37150084
17.
Capturing the reaction pathway in near-atomic-resolution crystal structures of HIV-1 protease.
Biochemistry
; 51(39): 7726-32, 2012 Oct 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-22963370
18.
Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors.
Bioorg Med Chem Lett
; 22(6): 2308-11, 2012 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22364812
19.
HIV-1 protease with 10 lopinavir and darunavir resistance mutations exhibits altered inhibition, structural rearrangements and extreme dynamics.
J Mol Graph Model
; 117: 108315, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36108568
20.
Design, Synthesis and X-Ray Structural Studies of Potent HIV-1 Protease Inhibitors Containing C-4 Substituted Tricyclic Hexahydro-Furofuran Derivatives as P2 Ligands.
ChemMedChem
; 17(9): e202200058, 2022 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35170223