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Novel difluoromethyl-containing 1-((4-methoxy-3-(piperazin-1-yl)phenyl)sulfonyl)-1H-indole scaffold as potent 5-HT6R antagonists: Design, synthesis, biological evaluation, and early in vivo cognition-enhancing studies.
Bioorg Med Chem
; 70: 116917, 2022 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35839536
2.
Novel difluoromethylated 1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-indole derivatives as potent 5-HT6 receptor antagonist with AMDE-improving properties: Design, synthesis, and biological evaluation.
Bioorg Med Chem
; 71: 116950, 2022 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35926324
3.
Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter.
J Med Chem
; 66(1): 371-383, 2023 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36598095
4.
Design, synthesis and biological evaluation of pyridinylmethylenepiperidine derivatives as potent 5-HT1F receptor agonists for migraine therapy.
Eur J Med Chem
; 225: 113782, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34419891
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