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1.
Attribution of the discrepancy between ELISA and LC-MS/MS assay results of a PEGylated scaffold protein in post-dose monkey plasma samples due to the presence of anti-drug antibodies.
Anal Bioanal Chem
; 402(3): 1229-39, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22130720
2.
Quantification of 4-beta-hydroxycholesterol in human plasma using automated sample preparation and LC-ESI-MS/MS analysis.
Chem Res Toxicol
; 24(9): 1575-85, 2011 Sep 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-21728364
3.
Novel tricyclic inhibitors of IKK2: discovery and SAR leading to the identification of 2-methoxy-N-((6-(1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl)pyridin-2-yl)methyl)acetamide (BMS-066).
Bioorg Med Chem Lett
; 21(23): 7006-12, 2011 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22018461
4.
Periodic, partial inhibition of IkappaB Kinase beta-mediated signaling yields therapeutic benefit in preclinical models of rheumatoid arthritis.
J Pharmacol Exp Ther
; 331(2): 349-60, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19652024
5.
Development and implementation of a stereoselective normal-phase liquid chromatography-tandem mass spectrometry method for the determination of intrinsic metabolic clearance in human liver microsomes.
J Chromatogr B Analyt Technol Biomed Life Sci
; 875(1): 154-60, 2008 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18722827
6.
Separation of maxi-K channel opening 3-substituted-4-arylquinolinone atropisomers by enantioselective supercritical fluid chromatography.
J Pharm Biomed Anal
; 48(4): 1120-6, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18922657
7.
Enantioselective chromatography in drug discovery.
Drug Discov Today
; 10(8): 571-7, 2005 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15837600
8.
Characterization of protein therapeutics by mass spectrometry: recent developments and future directions.
Drug Discov Today
; 16(1-2): 58-64, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21093608
9.
Chiral separation of potent corticotropin-releasing factor-1 receptor antagonists by supercritical fluid chromatography.
J Pharm Biomed Anal
; 54(3): 602-6, 2011 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-21036503
10.
A tris (2-carboxyethyl) phosphine (TCEP) related cleavage on cysteine-containing proteins.
J Am Soc Mass Spectrom
; 21(5): 837-44, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20189823
11.
Novel tricyclic inhibitors of IkappaB kinase.
J Med Chem
; 52(7): 1994-2005, 2009 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-19267461
12.
Simulated moving columns technique for enantioselective supercritical fluid chromatography.
Chirality
; 19(9): 683-92, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17487890
13.
High-throughput chiral analysis of albuterol enantiomers in dog plasma using on-line sample extraction/polar organic mode chiral liquid chromatography with tandem mass spectrometric detection.
Rapid Commun Mass Spectrom
; 18(21): 2531-6, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15468103
14.
Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
Bioorg Med Chem Lett
; 12(1): 45-9, 2002 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-11738570
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