Detalles de la búsqueda
1.
Preclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson Disease.
J Pharmacol Exp Ther
; 374(1): 113-125, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32358046
2.
The dopaminergic stabilizers pridopidine and ordopidine enhance cortico-striatal Arc gene expression.
J Neural Transm (Vienna)
; 121(11): 1337-47, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24817271
3.
Neurophysiological treatment effects of mesdopetam, pimavanserin and clozapine in a rodent model of Parkinson's disease psychosis.
Neurotherapeutics
; 21(2): e00334, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38368170
4.
The dopaminergic stabilizer pridopidine increases neuronal activity of pyramidal neurons in the prefrontal cortex.
J Neural Transm (Vienna)
; 120(9): 1281-94, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23468085
5.
Extrastriatal dopamine D(2) receptor binding in Huntington's disease.
Hum Brain Mapp
; 32(10): 1626-36, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20886576
6.
First-in-Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Pirepemat, a Cortical Enhancer, in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 10(12): 1485-1494, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34118179
7.
A first-in-human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers.
Pharmacol Res Perspect
; 9(3): e00792, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34018344
8.
Pridopidine: Overview of Pharmacology and Rationale for its Use in Huntington's Disease.
J Huntingtons Dis
; 7(1): 1-16, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29480206
9.
Relationships between free radical levels during carotid endarterectomy and markers of arteriosclerotic disease.
Int J Med Sci
; 4(3): 124-30, 2007 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-17505560
10.
In Vivo Systems Response Profiling and Multivariate Classification of CNS Active Compounds: A Structured Tool for CNS Drug Discovery.
ACS Chem Neurosci
; 8(4): 785-797, 2017 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27997108
11.
Altered pattern of brain dopamine synthesis in male adolescents with attention deficit hyperactivity disorder.
Behav Brain Funct
; 2: 40, 2006 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-17144907
12.
Behavioral Analysis of Dopaminergic Activation in Zebrafish and Rats Reveals Similar Phenotypes.
ACS Chem Neurosci
; 7(5): 633-46, 2016 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-26947759
13.
Antidopaminergic Medication is Associated with More Rapidly Progressive Huntington's Disease.
J Huntingtons Dis
; 4(2): 131-40, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26397894
14.
Effects of pretreatment with a xanthine oxidase inhibitor on free radical levels during carotid endarterectomy.
Free Radic Res
; 38(3): 283-93, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15129736
15.
Co-administration of the Dopaminergic Stabilizer Pridopidine and Tetrabenazine in Rats.
J Huntingtons Dis
; 3(3): 285-98, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25300332
16.
Synthesis, pharmacological evaluation and QSAR modeling of mono-substituted 4-phenylpiperidines and 4-phenylpiperazines.
Eur J Med Chem
; 62: 241-55, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23353756
17.
The dopaminergic stabilizer pridopidine decreases expression of L-DOPA-induced locomotor sensitisation in the rat unilateral 6-OHDA model.
Eur J Pharmacol
; 698(1-3): 278-85, 2013 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-23127496
18.
Concomitant release of ventral tegmental acetylcholine and accumbal dopamine by ghrelin in rats.
PLoS One
; 7(11): e49557, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23166710
19.
Synthesis and evaluation of a set of para-substituted 4-phenylpiperidines and 4-phenylpiperazines as monoamine oxidase (MAO) inhibitors.
J Med Chem
; 55(7): 3242-9, 2012 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22385498
20.
Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).
J Med Chem
; 53(6): 2510-20, 2010 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-20155917