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1.
Lack of pharmacokinetic interaction between the HIV-1 maturation inhibitor GSK3640254 and combination oral contraceptives in healthy women.
Br J Clin Pharmacol
; 88(4): 1704-1712, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34427938
2.
A Phase I Evaluation of the Pharmacokinetics and Tolerability of the HIV-1 Maturation Inhibitor GSK3640254 and Tenofovir Alafenamide/Emtricitabine in Healthy Participants.
Antimicrob Agents Chemother
; 65(6)2021 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33753329
3.
Phase I evaluation of pharmacokinetics and tolerability of the HIV-1 maturation inhibitor GSK3640254 and dolutegravir in healthy adults.
Br J Clin Pharmacol
; 87(9): 3501-3507, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33533507
4.
Hepatic Phospholipidosis Is Associated with Altered Hepatobiliary Function as Assessed by Gadoxetate Dynamic Contrast-enhanced Magnetic Resonance Imaging.
Toxicol Pathol
; 44(1): 51-60, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26516164
5.
Drug interaction profile of the HIV integrase inhibitor cabotegravir: assessment from in vitro studies and a clinical investigation with midazolam.
Xenobiotica
; 46(5): 445-56, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26340566
6.
In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.
Drug Metab Dispos
; 41(2): 353-61, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23132334
7.
Use of cassette dosing in sandwich-cultured rat and human hepatocytes to identify drugs that inhibit bile acid transport.
Toxicol In Vitro
; 24(1): 297-309, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19706322
8.
Temporal kinetics and concentration-response relationships for induction of CYP1A, CYP2B, and CYP3A in primary cultures of beagle dog hepatocytes.
J Biochem Mol Toxicol
; 20(2): 69-78, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-16615094
9.
In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates.
Drug Metab Dispos
; 34(5): 786-92, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16455806
10.
Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1.
Drug Metab Dispos
; 33(8): 1158-65, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15860656
11.
The systemic exposure of an N-methyl-D-aspartate receptor antagonist is limited in mice by the P-glycoprotein and breast cancer resistance protein efflux transporters.
Drug Metab Dispos
; 32(7): 722-6, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15205387
12.
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
J Pharmacol Exp Ther
; 303(3): 1029-37, 2002 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-12438524
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