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1.
Alcohol Pharmacology Education Partnership: Using Chemistry and Biology Concepts To Educate High School Students about Alcohol.
J Chem Educ
; 91(2): 165-172, 2014 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24803686
2.
Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development.
Cancer Cell
; 7(4): 313-24, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15837621
3.
Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques.
bioRxiv
; 2023 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37986885
4.
GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer.
J Clin Invest
; 117(5): 1294-304, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17476360
5.
Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells.
BMC Cancer
; 6: 60, 2006 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16539721
6.
Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.
J Biol Chem
; 283(32): 22257-71, 2008 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-18505730
7.
Liposomes comprising anionic but not neutral phospholipids cause dissociation of Rac(1 or 2) x RhoGDI complexes and support amphiphile-independent NADPH oxidase activation by such complexes.
J Biol Chem
; 281(28): 19204-19, 2006 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-16702219
8.
A novel protein geranylgeranyltransferase-I inhibitor with high potency, selectivity, and cellular activity.
J Biol Chem
; 281(18): 12445-50, 2006 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-16517596
9.
Activation of the phagocyte NADPH oxidase by Rac Guanine nucleotide exchange factors in conjunction with ATP and nucleoside diphosphate kinase.
J Biol Chem
; 280(5): 3802-11, 2005 Feb 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-15557278
10.
Transforming activity of the Rho family GTPase, Wrch-1, a Wnt-regulated Cdc42 homolog, is dependent on a novel carboxyl-terminal palmitoylation motif.
J Biol Chem
; 280(38): 33055-65, 2005 Sep 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-16046391
11.
A prenylated p67phox-Rac1 chimera elicits NADPH-dependent superoxide production by phagocyte membranes in the absence of an activator and of p47phox: conversion of a pagan NADPH oxidase to monotheism.
J Biol Chem
; 277(21): 18605-10, 2002 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-11896062
12.
The guanine nucleotide exchange factor trio activates the phagocyte NADPH oxidase in the absence of GDP to GTP exchange on Rac. "The emperor's nw clothes".
J Biol Chem
; 278(7): 4854-61, 2003 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-12475976
13.
Improved loading and cleavage methods for solid-phase synthesis using chlorotrityl resins: synthesis and testing of a library of 144 discrete chemicals as potential farnesyltransferase inhibitors.
J Comb Chem
; 6(3): 407-13, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15132601
14.
Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras.
J Biol Chem
; 279(16): 16007-16, 2004 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-14761978
15.
A tagging-via-substrate technology for detection and proteomics of farnesylated proteins.
Proc Natl Acad Sci U S A
; 101(34): 12479-84, 2004 Aug 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15308774
16.
High affinity for farnesyltransferase and alternative prenylation contribute individually to K-Ras4B resistance to farnesyltransferase inhibitors.
J Biol Chem
; 278(43): 41718-27, 2003 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-12882980
17.
Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver.
J Biol Chem
; 277(41): 38358-63, 2002 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-12151402
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