Detalles de la búsqueda
1.
Comprehensive characterization and optimization of Caco-2 cells enabled the development of a miniaturized 96-well permeability assay.
Xenobiotica
; 52(7): 742-750, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-36217915
2.
Ultrahigh-Throughput and Chromatography-Free Bioanalysis of Polar Analytes with Acoustic Ejection Mass Spectrometry.
Anal Chem
; 92(19): 13525-13531, 2020 10 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32926623
3.
A high-speed liquid chromatography/tandem mass spectrometry platform using multiplexed multiple-injection chromatography controlled by single software and its application in discovery ADME screening.
Rapid Commun Mass Spectrom
; 27(7): 731-7, 2013 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23495019
4.
Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen.
Rapid Commun Mass Spectrom
; 25(9): 1231-40, 2011 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21488121
5.
Enabling direct and definitive free fraction determination for highly-bound compounds in protein binding assay.
J Pharm Biomed Anal
; 194: 113765, 2021 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33272788
6.
Acoustic Ejection/Full-Scan Mass Spectrometry Analysis for High-Throughput Compound Quality Control.
SLAS Technol
; 26(2): 178-188, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33196338
7.
Rapid Compound Integrity Assessment for High-Throughput Screening Hit Triaging.
SLAS Discov
; 26(2): 242-247, 2021 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-32400264
8.
Microscale purification in support of high-throughput medicinal chemistry.
Chem Commun (Camb)
; 57(84): 11037-11040, 2021 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34608906
9.
An integrated bioanalytical platform for supporting high-throughput serum protein binding screening.
Rapid Commun Mass Spectrom
; 24(24): 3593-601, 2010 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-21080511
10.
Orthogonality of SFC versus HPLC for small molecule library separation.
J Comb Chem
; 12(6): 877-82, 2010 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-20923153
11.
A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen.
Rapid Commun Mass Spectrom
; 23(11): 1579-91, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19399765
12.
Optimization of microflow LC-MS/MS and its utility in quantitative discovery bioanalysis.
Bioanalysis
; 11(11): 1117-1127, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-31251100
13.
Addition of Optimized Bovine Serum Albumin Level in a High-Throughput Caco-2 Assay Enabled Accurate Permeability Assessment for Lipophilic Compounds.
SLAS Discov
; 24(7): 738-744, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31076010
14.
HPLC biogram analysis: a powerful tool used for hit confirmation in early drug discovery.
J Biomol Screen
; 20(5): 681-7, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25681433
15.
Comparative assessment of achiral stationary phases for high throughput analysis in supercritical fluid chromatography.
J Chromatogr A
; 1332: 73-81, 2014 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24508356
16.
Development of an LC-MS/MS method for high throughput quantification of metformin uptake in transporter inhibition assays.
J Chromatogr B Analyt Technol Biomed Life Sci
; 967: 211-8, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25125398
17.
Comparison of chromatographic techniques for diastereomer separation of a diverse set of drug-like compounds.
J Chromatogr A
; 1272: 150-4, 2013 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23261288
18.
Cassette incubation followed by bioanalysis using high-resolution MS for in vitro ADME screening assays.
Bioanalysis
; 4(5): 581-93, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22409555
19.
Addressing the medicinal chemistry bottleneck: a lean approach to centralized purification.
ACS Comb Sci
; 14(9): 520-6, 2012 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-22909004
20.
Approach to improve compound recovery in a high-throughput Caco-2 permeability assay supported by liquid chromatography-tandem mass spectrometry.
J Pharm Sci
; 101(8): 2755-62, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22611052