Detalles de la búsqueda
1.
Chronic Illness in Children and Foregone Care Among Household Adults in the United States: A National Study.
Med Care
; 61(4): 185-191, 2023 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36730827
2.
Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties.
Bioorg Med Chem Lett
; 30(14): 127214, 2020 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32527538
3.
Improving Access to Evidence-Based Medical Treatment for Opioid Use Disorder: Strategies to Address Key Barriers within the Treatment System.
NAM Perspect
; 20202020.
Artículo
en Inglés
| MEDLINE | ID: mdl-35291732
4.
Brain-penetrating 2-aminobenzimidazole H(1)-antihistamines for the treatment of insomnia.
Bioorg Med Chem Lett
; 19(15): 4380-4, 2009 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19553115
5.
Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy.
J Med Chem
; 51(3): 400-6, 2008 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-18189346
6.
2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 2. Reduction of hERG activity, observed species selectivity, and structure-activity relationships.
J Med Chem
; 51(6): 1730-9, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18307293
7.
Structure-activity relationship studies on a series of piperazinebenzylalcohols and their ketone and amine analogs as melanocortin-4 receptor ligands.
Bioorg Med Chem Lett
; 18(17): 4817-22, 2008 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18682322
8.
Design and synthesis of 3-arylpyrrolidine-2-carboxamide derivatives as melanocortin-4 receptor ligands.
Bioorg Med Chem Lett
; 18(6): 1931-8, 2008 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18294847
9.
Synthesis and structure-activity relationships of selective norepinephrine reuptake inhibitors (sNRI) with improved pharmaceutical characteristics.
Bioorg Med Chem Lett
; 18(23): 6151-5, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18954981
10.
Structure-activity relationships of chiral selective norepinephrine reuptake inhibitors (sNRI) with increased oxidative stability.
Bioorg Med Chem Lett
; 18(16): 4491-4, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18672364
11.
Potent and orally bioavailable zwitterion GnRH antagonists with low CYP3A4 inhibitory activity.
Bioorg Med Chem Lett
; 18(11): 3301-5, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18442910
12.
Identification and characterization of pyrrolidine diastereoisomers as potent functional agonists and antagonists of the human melanocortin-4 receptor.
Bioorg Med Chem Lett
; 18(1): 129-36, 2008 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18032040
13.
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties.
Bioorg Med Chem Lett
; 18(16): 4503-7, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18667310
14.
Pharmacological and pharmacokinetic characterization of 2-piperazine-alpha-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonists.
Bioorg Med Chem
; 16(10): 5606-18, 2008 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18417348
15.
Studies on the structure-activity relationship of the basic amine of phenylpiperazines as melanocortin-4 receptor antagonists.
Med Chem
; 4(1): 67-74, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18220971
16.
In vitro Drug Metabolism Investigation of 7-Ethoxycoumarin in Human, Monkey, Dog and Rat Hepatocytes by High Resolution LC-MS/MS.
Drug Metab Lett
; 12(1): 33-53, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29669508
17.
Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties.
J Med Chem
; 61(14): 6018-6033, 2018 07 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29886732
18.
Design, synthesis, in vitro, and in vivo characterization of phenylpiperazines and pyridinylpiperazines as potent and selective antagonists of the melanocortin-4 receptor.
J Med Chem
; 50(25): 6356-66, 2007 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-17994683
19.
Discovery of 1-[2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl]-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexia.
J Med Chem
; 50(22): 5249-52, 2007 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17918824
20.
Synthesis and characterization of pyrrolidine derivatives as potent agonists of the human melanocortin-4 receptor.
Bioorg Med Chem Lett
; 17(23): 6546-52, 2007 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17933528