Detalles de la búsqueda
1.
Alpibectir: Early Qualitative and Quantitative Metabolic Profiling from a First Time in Human Study by Combining 19F-NMR, 1H-NMR and HRMS Analyses.
Drug Metab Dispos
; 2024 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38769017
2.
A discovery biotransformation strategy: combining in silico tools with high-resolution mass spectrometry and software-assisted data analysis for high-throughput metabolism.
Xenobiotica
; 52(8): 928-942, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-36227740
3.
Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry.
Methods
; 82: 38-46, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25916617
4.
Direct determination of urinary creatinine by reactive-thermal desorption-extractive electrospray-ion mobility-tandem mass spectrometry.
Anal Chem
; 86(1): 357-61, 2014 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24279641
5.
Reactive metabolite trapping screens and potential pitfalls: bioactivation of a homomorpholine and formation of an unstable thiazolidine adduct.
Chem Res Toxicol
; 27(6): 968-80, 2014 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-24855970
6.
Direct detection of a sulfonate ester genotoxic impurity by atmospheric-pressure thermal desorption-extractive electrospray-mass spectrometry.
Anal Chem
; 85(13): 6224-7, 2013 Jul 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-23750985
7.
Enhanced analyte detection using in-source fragmentation of field asymmetric waveform ion mobility spectrometry-selected ions in combination with time-of-flight mass spectrometry.
Anal Chem
; 84(9): 4095-103, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22455620
8.
Direct extraction of urinary analytes from undeveloped reversed-phase thin layer chromatography plates using a solvent gradient combined with on-line electrospray ionisation ion mobility-mass spectrometry.
Analyst
; 137(15): 3510-3, 2012 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22724122
9.
Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism.
Xenobiotica
; 41(8): 720-34, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21671748
10.
Ambient ionization mass spectrometry: current understanding of mechanistic theory; analytical performance and application areas.
Analyst
; 135(4): 661-8, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20309440
11.
An approach to enhancing coverage of the urinary metabonome using liquid chromatography-ion mobility-mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 871(2): 357-61, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18502703
12.
On-line capillary column immobilised metal affinity chromatography/electrospray ionisation mass spectrometry for the selective analysis of histidine-containing peptides.
J Chromatogr B Analyt Technol Biomed Life Sci
; 857(2): 240-5, 2007 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17681498
13.
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.
J Med Chem
; 49(7): 2294-310, 2006 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-16570926
14.
Commentary: Challenging convention using ambient ionization and direct analysis mass spectrometric techniques.
Rapid Commun Mass Spectrom
; 25(6): 821-5, 2011 Mar 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-21337645
15.
Enhanced performance in the determination of ibuprofen 1-ß-O-acyl glucuronide in urine by combining high field asymmetric waveform ion mobility spectrometry with liquid chromatography-time-of-flight mass spectrometry.
J Chromatogr A
; 1278: 76-81, 2013 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23336944
16.
Conference Report: High-resolution MS in drug discovery and development: current applications and future perspectives.
Bioanalysis
; 4(5): 481-6, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22409547
17.
Evaluation of laser diode thermal desorption (LDTD) coupled with tandem mass spectrometry (MS/MS) for support of in vitro drug discovery assays: increasing scope, robustness and throughput of the LDTD technique for use with chemically diverse compound libraries.
J Pharm Biomed Anal
; 59: 18-28, 2012 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-22071442
18.
Determination of free desmosine and isodesmosine as urinary biomarkers of lung disorder using ultra performance liquid chromatography-ion mobility-mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 879(32): 3797-801, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22088351
19.
Analysis of pharmaceutical formulations using atmospheric pressure ion mobility spectrometry combined with liquid chromatography and nano-electrospray ionisation.
Analyst
; 132(1): 34-40, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17180177
20.
Analysis of tryptic peptides using desorption electrospray ionisation combined with ion mobility spectrometry/mass spectrometry.
Rapid Commun Mass Spectrom
; 21(7): 1131-8, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17318928