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1.
Synthesis and evaluation of 2-phenyl-1,4-butanediamine-based CCR5 antagonists for the treatment of HIV-1.
Bioorg Med Chem Lett
; 21(5): 1394-8, 2011 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21292480
2.
Discovery of a novel series of cyclic urea as potent CCR5 antagonists.
Bioorg Med Chem Lett
; 21(21): 6381-5, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21930378
3.
Discovery of novel pyridyl carboxamides as potent CCR5 antagonists and optimization of their pharmacokinetic profile in rats.
Bioorg Med Chem Lett
; 21(21): 6470-5, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21920742
4.
Blockade of X4-tropic HIV-1 cellular entry by GSK812397, a potent noncompetitive CXCR4 receptor antagonist.
Antimicrob Agents Chemother
; 54(2): 817-24, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19949058
5.
Synthesis and SAR of novel isoquinoline CXCR4 antagonists with potent anti-HIV activity.
Bioorg Med Chem Lett
; 20(10): 3026-30, 2010 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20443225
6.
Discovery of N-benzyl-N'-(4-pipyridinyl)urea CCR5 antagonists as anti-HIV-1 agents (I): optimization of the amine portion.
Bioorg Med Chem Lett
; 20(24): 7397-400, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21035337
7.
Discovery of N-benzyl-N'-(4-pipyridinyl)urea CCR5 antagonists as anti-HIV-1 agents (II): modification of the acyl portion.
Bioorg Med Chem Lett
; 20(24): 7401-4, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21055933
8.
Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents.
Bioorg Med Chem Lett
; 20(7): 2125-8, 2010 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20207537
9.
Synthesis of a novel tricyclic 1,2,3,4,4a,5,6,10b-octahydro-1,10-phenanthroline ring system and CXCR4 antagonists with potent activity against HIV-1.
Bioorg Med Chem Lett
; 20(7): 2186-90, 2010 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20194023
10.
[2-(4-Phenyl-4-piperidinyl)ethyl]amine based CCR5 antagonists: derivatizations at the N-terminal of the piperidine ring.
Bioorg Med Chem Lett
; 19(6): 1610-3, 2009 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19233649
11.
Imidazopyridine-5,6,7,8-tetrahydro-8-quinolinamine derivatives with potent activity against HIV-1.
Bioorg Med Chem Lett
; 19(22): 6399-403, 2009 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19818609
12.
Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors.
J Med Chem
; 58(7): 2967-87, 2015 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25760409
13.
Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile.
J Med Chem
; 54(11): 3756-67, 2011 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-21539377
14.
Discovery of bioavailable 4,4-disubstituted piperidines as potent ligands of the chemokine receptor 5 and inhibitors of the human immunodeficiency virus-1.
J Med Chem
; 51(20): 6538-46, 2008 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-18811134
15.
Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors.
Bioorg Med Chem Lett
; 15(15): 3560-4, 2005 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15975788
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