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1.
A phase 2a, randomized, double-blind, placebo-controlled, three-arm, parallel-group study to assess the efficacy, safety, tolerability and pharmacodynamics of PF-06835919 in patients with non-alcoholic fatty liver disease and type 2 diabetes.
Diabetes Obes Metab
; 25(4): 992-1001, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36515213
2.
An 8-Week, Randomized, Phase 2, Double-Blind, Sequential Parallel-Group Comparison Study of Two Dose Levels of the GABAA Positive Allosteric Modulator PF-06372865 Compared With Placebo as an Adjunctive Treatment in Outpatients With Inadequate Response to Standard of Care for Generalized Anxiety Disorder.
J Clin Psychopharmacol
; 39(1): 20-27, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30531477
3.
Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABAA partial agonist, in humans.
Br J Anaesth
; 123(2): e194-e203, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30915991
4.
Response to "Treating patients rather than their functional neuroimages" (Br J Anaesth 2018; 121: 969-71).
Br J Anaesth
; 123(2): e166-e171, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30979518
5.
Characterization, optimisation and process robustness of a co-processed mannitol for the development of orally disintegrating tablets.
Pharm Dev Technol
; 18(1): 172-85, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22582882
6.
Mixed meal tolerance testing highlights in diabetes altered branched-chain ketoacid metabolism and pathways associated with all-cause mortality.
Am J Clin Nutr
; 117(3): 529-539, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36811472
7.
Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Intravenous Infusions of PF-07304814 (Lufotrelvir) in Participants Hospitalized With COVID-19.
Open Forum Infect Dis
; 10(8): ofad355, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37559753
8.
Safety, Tolerability, and Pharmacokinetics of Multiple Repeated Oral Doses of the α2/3/5-Subtype Selective GABAA -Positive Allosteric Modulator PF-06372865 in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 10(7): 756-764, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33465277
9.
Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies.
Innov Clin Neurosci
; 16(7-08): 12-17, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31832258
10.
Photosensitive epilepsy: Robust clinical efficacy of a selective GABA potentiator.
Neurology
; 92(15): e1786-e1795, 2019 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30877186
11.
Induced hepatic fibrosis in rats: hepatic steatosis, macromolecule content, perfusion parameters, and their correlations--preliminary MR imaging in rats.
Radiology
; 247(3): 696-705, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18403622
12.
Raman mapping of low-content active-ingredient pharmaceutical formulations. part II: statistically optimized sampling for detection of less than 1% of an active pharmaceutical ingredient.
Appl Spectrosc
; 62(8): 916-21, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18702866
13.
Audio Recording for Independent Confirmation of Clinical Assessments in Generalized Anxiety Disorder.
Innov Clin Neurosci
; 15(3-4): 37-42, 2018 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29721364
14.
A randomised, placebo-controlled clinical trial with the α2/3/5 subunit selective GABAA positive allosteric modulator PF-06372865 in patients with chronic low back pain.
Pain
; 159(9): 1742-1751, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29787472
15.
Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration.
Nat Biotechnol
; 36(4): 328-337, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29553577
16.
Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF-06372865.
Br J Pharmacol
; 175(4): 708-725, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29214652
17.
Learning to identify CNS drug action and efficacy using multistudy fMRI data.
Sci Transl Med
; 7(274): 274ra16, 2015 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-25673761
18.
The scientific basis for the duration of stability data required at the time of submission.
J Pharm Sci
; 99(6): 2538-43, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20049942
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