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1.
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities.
Chem Res Toxicol
; 35(3): 475-489, 2022 03 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35212515
2.
Framework for sensitization assessment of extractables and leachables in pharmaceuticals.
Crit Rev Toxicol
; 52(2): 125-138, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35703156
3.
An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury.
Arch Toxicol
; 95(1): 149-168, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32816093
4.
Enzalutamide and Apalutamide: In Vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy Model.
Chem Res Toxicol
; 33(1): 211-222, 2020 01 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31538772
5.
New Approaches to Investigate Drug-Induced Hypersensitivity.
Chem Res Toxicol
; 30(1): 239-259, 2017 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27806199
6.
Identification of MHC Haplotypes Associated with Drug-induced Hypersensitivity Reactions in Cynomolgus Monkeys.
Toxicol Pathol
; 45(1): 127-133, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27879435
7.
Drug-induced Skin Lesions in Cynomolgus Macaques Treated with Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulators.
Toxicol Pathol
; 43(7): 995-1003, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26059827
8.
Drug hypersensitivity reactions: review of the state of the science for prediction and diagnosis.
Toxicol Sci
; 2024 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38588579
9.
Sensitization Assessment of Extractables and Leachables in Pharmaceuticals: ELSIE Database Analysis.
PDA J Pharm Sci Technol
; 2023 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37714567
10.
Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays.
Lab Chip
; 20(2): 199-214, 2020 01 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31598618
11.
Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators.
Cell Chem Biol
; 24(7): 858-869.e5, 2017 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28669525
12.
Development of a modified lymphocyte transformation test for diagnosing drug-induced liver injury associated with an adaptive immune response.
J Immunotoxicol
; 14(1): 31-38, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28121193
13.
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.
J Med Chem
; 60(18): 7764-7780, 2017 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-28817277
14.
Characterization of the draining lymph node response in the mouse drug allergy model: A model for drug hypersensitivity reactions.
J Immunotoxicol
; 12(4): 376-84, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25469456
15.
Development and partial validation of a mouse model for predicting drug hypersensitivity reactions.
J Immunotoxicol
; 11(2): 141-7, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-23879792
16.
Development of a screening assay to evaluate the potential of drugs to cause immune-mediated hypersensitivity reactions.
J Immunotoxicol
; 11(2): 110-5, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-23768081
17.
Non-coplanar polychlorinated biphenyl (PCB)-induced immunotoxicity is coincident with alterations in the serotonergic system.
J Immunotoxicol
; 7(4): 318-26, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-20843273
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