Detalles de la búsqueda
1.
High-throughput selection of (new) enzymes: phage display-mediated isolation of alkyl halide hydrolases from a library of active-site mutated epoxide hydrolases.
Faraday Discuss
; 2024 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38828992
2.
Structure and Mechanism of a Cold-Adapted Bacterial Lipase.
Biochemistry
; 61(10): 933-942, 2022 05 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35503728
3.
Facile synthesis of 2-hydroxyacetophenone from racemic styrene oxide catalyzed by engineered enzymes.
Biotechnol Lett
; 44(8): 985-990, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35731351
4.
Chemical and Biochemical Approaches for the Synthesis of Substituted Dihydroxybutanones and Di- and Tri-Hydroxypentanones.
J Org Chem
; 84(11): 6982-6991, 2019 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31066559
5.
Crystal structure and pH-dependent allosteric regulation of human ß-ureidopropionase, an enzyme involved in anticancer drug metabolism.
Biochem J
; 475(14): 2395-2416, 2018 07 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-29976570
6.
New Stereoselective Biocatalysts for Carboligation and Retro-Aldol Cleavage Reactions Derived from d-Fructose 6-Phosphate Aldolase.
Biochemistry
; 57(40): 5877-5885, 2018 10 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30204427
7.
Directed Evolution of Alcohol Dehydrogenase for Improved Stereoselective Redox Transformations of 1-Phenylethane-1,2-diol and Its Corresponding Acyloin.
Biochemistry
; 57(7): 1059-1062, 2018 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29384657
8.
Laboratory-Evolved Enzymes Provide Snapshots of the Development of Enantioconvergence in Enzyme-Catalyzed Epoxide Hydrolysis.
Chembiochem
; 17(18): 1693-7, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27383542
9.
A Microplate Format Assay for Real-Time Screening for New Aldolases that Accept Aryl-Substituted Acceptor Substrates.
Chembiochem
; 16(18): 2595-8, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26449620
10.
Structural enzymology studies with the substrate 3S-hydroxybutanoyl-CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD.
FEBS Open Bio
; 14(4): 655-674, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38458818
11.
Exploring the active site of tripeptidyl-peptidase II through studies of pH dependence of reaction kinetics.
Biochim Biophys Acta
; 1824(4): 561-70, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22266401
12.
Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics.
FEBS J
; 290(2): 465-481, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36002154
13.
Crystal structures and kinetic studies of a laboratory evolved aldehyde reductase explain the dramatic shift of its new substrate specificity.
IUCrJ
; 10(Pt 4): 437-447, 2023 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37261425
14.
Obtaining optical purity for product diols in enzyme-catalyzed epoxide hydrolysis: contributions from changes in both enantio- and regioselectivity.
Biochemistry
; 51(38): 7627-37, 2012 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22931287
15.
Correction to Obtaining Optical Purity for Product Diols in Enzyme-Catalyzed Epoxide Hydrolysis: Contributions from Changes in both Enantio- and Regioselectivity.
Biochemistry
; 55(12): 1940, 2016 Mar 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-26986896
16.
Structure-function relationships of epoxide hydrolases and their potential use in biocatalysis.
Biochim Biophys Acta
; 1800(3): 316-26, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19948209
17.
Temperature and pH dependence of enzyme-catalyzed hydrolysis of trans-methylstyrene oxide. A unifying kinetic model for observed hysteresis, cooperativity, and regioselectivity.
Biochemistry
; 49(10): 2297-304, 2010 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-20146441
18.
Modification of substrate specificity resulting in an epoxide hydrolase with shifted enantiopreference for (2,3-epoxypropyl)benzene.
Chembiochem
; 11(10): 1422-9, 2010 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-20544772
19.
Mutations in salt-bridging residues at the interface of the core and lid domains of epoxide hydrolase StEH1 affect regioselectivity, protein stability and hysteresis.
Arch Biochem Biophys
; 495(2): 165-73, 2010 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20079707
20.
Engineering aldolases for asymmetric synthesis.
Methods Enzymol
; 644: 149-167, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32943143