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1.
Synthetic lethality between PAXX and XLF in mammalian development.
Genes Dev
; 30(19): 2152-2157, 2016 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27798842
2.
C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption.
Nat Commun
; 14(1): 5003, 2023 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37591890
3.
ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib.
Cancer Res
; 82(6): 1140-1152, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35078817
4.
Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance.
Clin Cancer Res
; 28(20): 4536-4550, 2022 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35921524
5.
Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development.
Mol Cancer Ther
; 20(9): 1614-1626, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34158341
6.
Combined PARP and ATR inhibition potentiates genome instability and cell death in ATM-deficient cancer cells.
Oncogene
; 39(25): 4869-4883, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32444694
7.
Publisher Correction: p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.
Nat Med
; 30(5): 1506, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38332041
8.
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.
Nat Commun
; 10(1): 5065, 2019 11 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31699977
9.
The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.
Sci Rep
; 8(1): 17891, 2018 12 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-30559450
10.
Author Correction: C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption.
Nat Commun
; 14(1): 7784, 2023 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38012134
11.
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.
Nat Med
; 22(8): 861-8, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27376578
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