Detalles de la búsqueda
1.
Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease.
Alzheimers Dement
; 19(5): 2084-2094, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36349985
2.
P2X7-mediated alteration of membrane fluidity is associated with the late stages of age-related macular degeneration.
Purinergic Signal
; 18(4): 469-479, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36001279
3.
Flow cytometry identifies an early stage of platelet apoptosis produced by agonists of the P2X1 and P2X7 receptors.
Platelets
; 33(4): 621-631, 2022 May 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35042433
4.
Genomics of Alzheimer's disease implicates the innate and adaptive immune systems.
Cell Mol Life Sci
; 78(23): 7397-7426, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34708251
5.
Identification of Leukocyte Surface P2X7 as a Biomarker Associated with Alzheimer's Disease.
Int J Mol Sci
; 23(14)2022 Jul 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35887215
6.
A P2RX7 single nucleotide polymorphism haplotype promotes exon 7 and 8 skipping and disrupts receptor function.
FASEB J
; 34(3): 3884-3901, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32003498
7.
The scavenger activity of the human P2X7 receptor differs from P2X7 pore function by insensitivity to antagonists, genetic variation and sodium concentration: Relevance to inflammatory brain diseases.
Biochim Biophys Acta Mol Basis Dis
; 1864(4 Pt A): 1051-1059, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29329985
8.
Loss of Function of P2X7 Receptor Scavenger Activity in Aging Mice: A Novel Model for Investigating the Early Pathogenesis of Age-Related Macular Degeneration.
Am J Pathol
; 187(8): 1670-1685, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28628761
9.
Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis.
Hum Mutat
; 38(6): 736-744, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28326637
10.
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis.
Hum Mol Genet
; 24(19): 5644-54, 2015 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26188005
11.
Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model.
Blood
; 126(26): 2863-70, 2015 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26450986
12.
Innate phagocytosis by peripheral blood monocytes is altered in Alzheimer's disease.
Acta Neuropathol
; 132(3): 377-89, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27411339
13.
P2X7 receptors mediate innate phagocytosis by human neural precursor cells and neuroblasts.
Stem Cells
; 33(2): 526-41, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25336287
14.
A quantitative method for measuring innate phagocytosis by human monocytes using real-time flow cytometry.
Cytometry A
; 85(4): 313-21, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24132941
15.
A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration.
FASEB J
; 27(4): 1479-87, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23303206
16.
P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid.
J Biol Chem
; 287(21): 17318-17330, 2012 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-22461619
17.
The role of the P2X7 receptor in infectious diseases.
PLoS Pathog
; 7(11): e1002212, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22102807
18.
P2X(7) is a scavenger receptor for apoptotic cells in the absence of its ligand, extracellular ATP.
J Immunol
; 187(5): 2365-75, 2011 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21821797
19.
The P2X7-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP.
Blood
; 115(8): 1621-31, 2010 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-20007545
20.
A new role for the P2X7 receptor: a scavenger receptor for bacteria and apoptotic cells in the absence of serum and extracellular ATP.
Purinergic Signal
; 8(3): 579-86, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22476940