Búsqueda | Biblioteca Virtual en Salud

1.

NOV03 for Dry Eye Disease Associated with Meibomian Gland Dysfunction: Results of the Randomized Phase 3 GOBI Study.

Tauber, Joseph; Berdy, Gregg J; Wirta, David L; Krösser, Sonja; Vittitow, Jason L.

Ophthalmology ; 130(5): 516-524, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-36574848

2.

Efficacy and Safety of OC-01 (Varenicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease: The ONSET-2 Phase 3 Randomized Trial.

Wirta, David; Vollmer, Patrick; Paauw, James; Chiu, Kuei-Hsun; Henry, Eugenia; Striffler, Kristen; Nau, Jeffrey.

Ophthalmology ; 129(4): 379-387, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-34767866

3.

Noninferiority Study Comparing Latanoprost 0.005% Without Versus With Benzalkonium Chloride in Open-Angle Glaucoma or Ocular Hypertension.

Wirta, David; Malhotra, Ranjan; Peace, James; Shen Lee, Bridgitte; Mitchell, Brittany; Sall, Kenneth; McMenemy, Matthew.

Eye Contact Lens ; 48(4): 149-154, 2022 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-35296626

4.

24-Hour Intraocular Pressure Control with Fixed-dose Combination Brinzolamide 1%/Brimonidine 0.2%: A Multicenter, Randomized Trial.

Weinreb, Robert N; Bacharach, Jason; Fechtner, Robert D; Kahook, Malik Y; Wirta, David; Burmaster, Steve; Meng, Xiangyi; Hubatsch, Douglas A.

Ophthalmology ; 126(8): 1095-1104, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-30403988

5.

A Clinical Phase II Study to Assess Efficacy, Safety, and Tolerability of Waterfree Cyclosporine Formulation for Treatment of Dry Eye Disease.

Wirta, David L; Torkildsen, Gail L; Moreira, Helen R; Lonsdale, John D; Ciolino, Joseph B; Jentsch, Garrit; Beckert, Michael; Ousler, George W; Steven, Philipp; Krösser, Sonja.

Ophthalmology ; 126(6): 792-800, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30703441

6.

Update on Dry Eye Disease.

Wirta, David.

JAMA ; 327(23): 2355-2356, 2022 06 21.

Artículo en Inglés | MEDLINE | ID: mdl-35727283

7.

Double-Masked, Vehicle-Controlled, Randomized, Phase II Study of the Ocular Hypotensive Activity and Safety of VVN539 Ophthalmic Solution.

Wirta, David; Li, Xiao-Yan; Shen, Wang; Lu, Caroline; Novack, Gary D.

Ophthalmol Sci ; 4(2): 100426, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38192683

8.

Omidenepag Isopropyl Versus Timolol in Patients With Glaucoma or Ocular Hypertension: Two Randomized Phase 3 Trials (SPECTRUM 4 and 3).

Bacharach, Jason; Brubaker, Jacob W; Evans, David G; Lu, Fenghe; Odani-Kawabata, Noriko; Yamabe, Takaharu; Wirta, David L.

Am J Ophthalmol ; 263: 23-34, 2024 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-38395329

9.

Long-Term Safety and Efficacy of a Water-Free Cyclosporine 0.1% Ophthalmic Solution for Treatment of Dry Eye Disease: ESSENCE-2 OLE.

Wirta, David L; Galor, Anat; Aune, Carol A; Vollmer, Patrick M; Liang, Eva; Meides, Alice S; Krösser, Sonja.

Cornea ; 2024 May 21.

Artículo en Inglés | MEDLINE | ID: mdl-38771801

10.

Patient-reported outcomes of bimatoprost for eyelash growth: results from a randomized, double-masked, vehicle-controlled, parallel-group study.

Fagien, Steven; Walt, John G; Carruthers, Jean; Cox, Sue Ellen; Wirta, David; Weng, Emily; Beddingfield, Frederick C.

Aesthet Surg J ; 33(6): 789-98, 2013 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-23873891

11.

Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis: Results of a Prospective, Randomized, Vehicle-Controlled, Double-Masked, Pivotal Trial (Saturn-1).

Yeu, Elizabeth; Wirta, David L; Karpecki, Paul; Baba, Stephanie N; Holdbrook, Mark.

Cornea ; 42(4): 435-443, 2023 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-35965392

12.

Two Randomized, Double-masked, Placebo-controlled Studies of the Local Anesthetic Effect of Articaine Ophthalmic Solution.

Gonzalez, Victor H; Wirta, David L; Uram, Martin; Schupp, Audrey; Widmann, Michelle; Novack, Gary D.

Clin Ophthalmol ; 17: 1357-1365, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37192994

13.

Safety and Target Engagement of Complement C1q Inhibitor ANX007 in Neurodegenerative Eye Disease: Results from Phase I Studies in Glaucoma.

Sun, Yang; Wirta, David; Murahashi, Wendy; Mathur, Vidhu; Sankaranarayanan, Sethu; Taylor, Lori K; Yednock, Ted; Fong, Donald S; Goldberg, Jeffrey L.

Ophthalmol Sci ; 3(2): 100290, 2023 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-37124168

14.

Single Administration of Bimatoprost Implant: Effects on 24-Hour Intraocular Pressure and 1-Year Outcomes.

Weinreb, Robert N; Christie, William C; Medeiros, Felipe A; Craven, E Randy; Kim, Kimmie; Nguyen, Ashley; Bejanian, Marina; Wirta, David L.

Ophthalmol Glaucoma ; 6(6): 599-608, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37343625

15.

Efficacy and Safety of a Water-Free Topical Cyclosporine, 0.1%, Solution for the Treatment of Moderate to Severe Dry Eye Disease: The ESSENCE-2 Randomized Clinical Trial.

Akpek, Esen K; Wirta, David L; Downing, Johnathon E; Tauber, Joseph; Sheppard, John D; Ciolino, Joseph B; Meides, Alice S; Krösser, Sonja.

JAMA Ophthalmol ; 141(5): 459-466, 2023 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-37022717

16.

Phase 2b, Randomized, 3-Month, Dose-Finding Study of Sepetaprost in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: The ANGEL Study.

Wirta, David L; Kuwayama, Yasuaki; Lu, Fenghe; Shao, Hui; Odani-Kawabata, Noriko.

J Ocul Pharmacol Ther ; 38(3): 240-251, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35167779

17.

A Comparison of TearCare and Lipiflow Systems in Reducing Dry Eye Disease Symptoms Associated with Meibomian Gland Disease.

Holland, Edward J; Loh, Jennifer; Bloomenstein, Marc; Thompson, Vance; Wirta, David; Dhamdhere, Kavita.

Clin Ophthalmol ; 16: 2861-2871, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36065356

18.

Safety and Efficacy of AGN-190584 in Individuals With Presbyopia: The GEMINI 1 Phase 3 Randomized Clinical Trial.

Waring, George O; Price, Francis W; Wirta, David; McCabe, Cathleen; Moshirfar, Majid; Guo, Qiang; Gore, Anu; Liu, Haixia; Safyan, Eleonora; Robinson, Michael R.

JAMA Ophthalmol ; 140(4): 363-371, 2022 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-35238902

19.

A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1).

Wirta, David L; Senchyna, Michelle; Lewis, Amber E; Evans, David G; McLaurin, Eugene B; Ousler, George W; Hollander, David A.

Ocul Surf ; 26: 166-173, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-35970431

20.

ONSET-1 Phase 2b Randomized Trial to Evaluate the Safety and Efficacy of OC-01 (Varenicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease.

Wirta, David; Torkildsen, Gail L; Boehmer, Blair; Hollander, David A; Bendert, Edward; Zeng, Lijuan; Ackermann, Michael; Nau, Jeffrey.

Cornea ; 41(10): 1207-1216, 2022 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-36107843

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