Detalles de la búsqueda
1.
Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N-Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression.
J Pharmacol Exp Ther
; 361(1): 68-86, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28138040
2.
The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits.
J Pharmacol Exp Ther
; 358(1): 71-82, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27189960
3.
M1 and m2 muscarinic receptor subtypes regulate antidepressant-like effects of the rapidly acting antidepressant scopolamine.
J Pharmacol Exp Ther
; 351(2): 448-56, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25187432
4.
Perampanel, an antagonist of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, for the treatment of epilepsy: studies in human epileptic brain and nonepileptic brain and in rodent models.
J Pharmacol Exp Ther
; 351(1): 124-33, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25027316
5.
In vivo occupancy of dopamine D3 receptors by antagonists produces neurochemical and behavioral effects of potential relevance to attention-deficit-hyperactivity disorder.
J Pharmacol Exp Ther
; 344(2): 501-10, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23197772
6.
Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia.
Proc Natl Acad Sci U S A
; 105(31): 10978-83, 2008 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-18678919
7.
R-(-)-ketamine modifies behavioral effects of morphine predicting efficacy as a novel therapy for opioid use disorder1.
Pharmacol Biochem Behav
; 194: 172927, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32333922
8.
The α2,3-selective potentiators of GABAA receptors, KRM-II-81 and MP-III-80, produce anxiolytic-like effects and block chemotherapy-induced hyperalgesia in mice without tolerance development.
Pharmacol Biochem Behav
; 196: 172996, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32668266
9.
The α2,3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats.
Pharmacol Biochem Behav
; 180: 22-31, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30825491
10.
The dopamine D3/D2 agonist (+)-PD-128,907 [(R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol)] protects against acute and cocaine-kindled seizures in mice: further evidence for the involvement of D3 receptors.
J Pharmacol Exp Ther
; 326(3): 930-8, 2008 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-18566292
11.
An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors.
Pharmacol Biochem Behav
; 170: 9-13, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29715490
12.
Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABAA receptors: Improved bioavailability enhances anticonvulsant efficacy.
Neuropharmacology
; 137: 332-343, 2018 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29778948
13.
Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors.
Pharmacol Biochem Behav
; 157: 35-40, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28442369
14.
Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects.
Pharmacol Biochem Behav
; 155: 43-55, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28285123
15.
Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders.
Trends Pharmacol Sci
; 20(3): 107-12, 1999 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-10203866
16.
AMPA receptor potentiators as novel antidepressants.
Curr Pharm Des
; 11(12): 1511-27, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15892659
17.
Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous system.
Pharmacol Ther
; 103(1): 1-20, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15251226
18.
Pharmacotherapy of cocaine abuse: preclinical development.
Neurosci Biobehav Rev
; 18(1): 121-42, 1994.
Artículo
en Inglés
| MEDLINE | ID: mdl-8170620
19.
Selective D3 receptor agonist effects of (+)-PD 128907 on dialysate dopamine at low doses.
Neuropharmacology
; 41(3): 351-9, 2001 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-11522326
20.
Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate.
Neuropharmacology
; 39(7): 1184-96, 2000 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-10760361