Detalles de la búsqueda
1.
Ultrasensitive liquid chromatography-tandem mass spectrometric methodologies for quantification of five HIV-1 integrase inhibitors in plasma for a microdose clinical trial.
Anal Chem
; 84(20): 8614-21, 2012 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23030780
2.
Evaluation of dried blood spot (DBS) technology versus plasma analysis for the determination of MK-1775 by HILIC-MS/MS in support of clinical studies.
Anal Bioanal Chem
; 404(10): 3037-48, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23099526
3.
Incorporating protein precipitation to resolve hybrid IP-LC-MS assay interference for ultrasensitive quantification of intact therapeutic insulin dimer in human plasma.
J Pharm Biomed Anal
; 212: 114639, 2022 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35176654
4.
Volumetric absorptive microsampling (VAMS®) in therapeutic protein quantification by LC-MS/MS: Investigation of anticoagulant impact on assay performance and recommendations for best practices in method development.
J Pharm Biomed Anal
; 196: 113895, 2021 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-33486450
5.
Immunoaffinity purification using anti-PEG antibody followed by two-dimensional liquid chromatography/tandem mass spectrometry for the quantification of a PEGylated therapeutic peptide in human plasma.
Anal Chem
; 82(16): 6877-86, 2010 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20704377
6.
Hydrophilic interaction chromatography/tandem mass spectrometry for the simultaneous determination of three polar non-structurally related compounds, imipenem, cilastatin and an investigational beta-lactamase inhibitor, MK-4698, in biological matrices.
Rapid Commun Mass Spectrom
; 23(14): 2195-205, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19530150
7.
Toward highly sensitive and reproducible LC-MS/MS analysis of MK-8591 phosphorylated anabolites in human peripheral blood mononuclear cells.
Bioanalysis
; 11(4): 233-250, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30767560
8.
Determination of a novel gamma-secretase inhibitor in human plasma and cerebrospinal fluid using automated 96 well solid phase extraction and liquid chromatography/tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
; 863(1): 36-45, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18249589
9.
Determination of sitagliptin in human urine and hemodialysate using turbulent flow online extraction and tandem mass spectrometry.
J Pharm Biomed Anal
; 46(3): 534-42, 2008 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-18096349
10.
Strategy for peptide quantification using LC-MS in regulated bioanalysis: case study with a glucose-responsive insulin.
Bioanalysis
; 10(15): 1207-1220, 2018 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30062907
11.
Extractability-mediated stability bias and hematocrit impact: High extraction recovery is critical to feasibility of volumetric adsorptive microsampling (VAMS) in regulated bioanalysis.
J Pharm Biomed Anal
; 156: 58-66, 2018 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29689469
12.
Novel Application of the Two-Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin.
Clin Transl Sci
; 11(4): 405-411, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29575530
13.
Insulin glargine and its two active metabolites: A sensitive (16pM) and robust simultaneous hybrid assay coupling immunoaffinity purification with LC-MS/MS to support biosimilar clinical studies.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1063: 50-59, 2017 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28846865
14.
Concerns in the development of an assay for determination of a highly conjugated adsorption-prone compound in human urine.
J Chromatogr B Analyt Technol Biomed Life Sci
; 818(2): 241-8, 2005 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-15734165
15.
A device for dried blood microsampling in quantitative bioanalysis: overcoming the issues associated blood hematocrit.
Bioanalysis
; 7(6): 653-9, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25514576
16.
Indinavir and rifabutin drug interactions in healthy volunteers.
J Clin Pharmacol
; 44(3): 305-13, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-14973305
17.
The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.
J Clin Pharmacol
; 44(10): 1125-31, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15342613
18.
Pharmacokinetics of etoricoxib in patients with hepatic impairment.
J Clin Pharmacol
; 43(10): 1136-48, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-14517196
19.
Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man.
J Clin Pharmacol
; 43(3): 268-76, 2003 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-12638395
20.
Pharmacokinetics of etoricoxib in patients with renal impairment.
J Clin Pharmacol
; 44(1): 48-58, 2004 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-14681341