Detalles de la búsqueda
1.
Cascade-Activated AIEgen-Peptide Probe for Noninvasively Monitoring Chymotrypsin-like Activity of Proteasomes in Cancer Cells.
Anal Chem
; 95(23): 9097-9106, 2023 06 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37249373
2.
A Dual-Responsive Morphologically-Adaptable Nanoplatform for Targeted Delivery of Activatable Photosensitizers in Precision Photodynamic Therapy.
Small
; : e2309054, 2023 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38081131
3.
Design, synthesis, and evaluation of novel pyridone derivatives as potent BRD4 inhibitors for the potential treatment of prostate cancer.
Bioorg Chem
; 119: 105575, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34995979
4.
Association of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of carotid atherosclerosis: a cross-sectional analysis of 730 Chinese Han adults in Chongqing.
BMC Cardiovasc Disord
; 20(1): 222, 2020 05 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32404177
5.
Discovery of trans-3-(pyridin-3-yl)acrylamide-derived sulfamides as potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitors for the potential treatment of cancer.
Bioorg Med Chem Lett
; 29(12): 1502-1506, 2019 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30992165
6.
First report of Ehrlichia infection in goats, China.
Microb Pathog
; 110: 275-278, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28705746
7.
Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure.
J Transl Med
; 13: 155, 2015 May 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25964118
8.
Copper-catalyzed trifluoromethylation of trisubstituted allylic and homoallylic alcohols.
Chemistry
; 21(18): 6700-3, 2015 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-25810003
9.
Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia.
J Med Chem
; 67(2): 1513-1532, 2024 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38175809
10.
Development of Son of Sevenless Homologue 1 (SOS1) Modulators To Treat Cancers by Regulating RAS Signaling.
J Med Chem
; 66(7): 4324-4341, 2023 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36987571
11.
High-Throughput Screening of Stapled Helical Peptides in Drug Discovery.
J Med Chem
; 66(1): 95-106, 2023 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36580278
12.
Identification of a Novel, Potent, and Orally Bioavailable Guanidine-Based SHP2 Allosteric Inhibitor from Virtual Screening and Rational Structural Optimization for the Treatment of KRAS Mutant Cancers.
J Med Chem
; 66(19): 13646-13664, 2023 10 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37754066
13.
Design and Synthesis of Sulfonium Derivatives: A Novel Class of α-Glucosidase Inhibitors with Potent In Vivo Antihyperglycemic Activities.
J Med Chem
; 66(5): 3484-3498, 2023 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36812150
14.
Corrigendum to 'Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)' [Genes Dis 8 (2021) 814-826].
Genes Dis
; 10(2): 618-619, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-37223499
15.
Small-molecule inhibitors targeting small ubiquitin-like modifier pathway for the treatment of cancers and other diseases.
Eur J Med Chem
; 233: 114227, 2022 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35247754
16.
Discovery of a Novel Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2) and Cyclin-Dependent Kinase 4 (CDK4) Dual Inhibitor for the Treatment of Triple-Negative Breast Cancer.
J Med Chem
; 65(9): 6729-6747, 2022 05 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35447031
17.
Enzymatic Synthesis of Peptide Nanofibers for Self-Delivery of Indomethacin and Tyroservatide in Cancer Therapy.
ACS Biomater Sci Eng
; 8(7): 3010-3021, 2022 07 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35679601
18.
Long short-term memory model - A deep learning approach for medical data with irregularity in cancer predication with tumor markers.
Comput Biol Med
; 144: 105362, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35299045
19.
A single phosphine ligand allows palladium-catalyzed intermolecular C-O bond formation with secondary and primary alcohols.
Angew Chem Int Ed Engl
; 50(42): 9943-7, 2011 Oct 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-21913292
20.
Radical-mediated vicinal addition of alkoxysulfonyl/fluorosulfonyl and trifluoromethyl groups to aryl alkyl alkynes.
Chem Sci
; 12(35): 11762-11768, 2021 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34659713