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1.
Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia.
Glia
; 65(7): 1103-1118, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28370426
2.
γ-Secretase in microglia - implications for neurodegeneration and neuroinflammation.
J Neurochem
; 143(4): 445-454, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28940294
3.
Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).
J Neuroinflammation
; 13: 17, 2016 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26792193
4.
Phosphorylation of the amyloid ß-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.
Acta Neuropathol
; 131(4): 525-37, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26898910
5.
Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage.
J Biol Chem
; 288(46): 33027-36, 2013 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24078628
6.
GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells.
Biochem Biophys Res Commun
; 450(1): 160-5, 2014 Jul 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-24866237
7.
Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-ß generation.
Am J Pathol
; 180(6): 2404-16, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22510327
8.
Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.
J Biol Chem
; 285(48): 37405-14, 2010 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-20876579
9.
Proteolytic processing of the serine protease matriptase-2: identification of the cleavage sites required for its autocatalytic release from the cell surface.
Biochem J
; 430(1): 87-95, 2010 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20518742
10.
Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology.
Int J Dev Neurosci
; 22(7): 475-84, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15465277
11.
APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.
Stem Cell Reports
; 1(6): 491-8, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24371804
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