Detalles de la búsqueda
1.
Targeting hypoxia-inducible factor-1, for cancer treatment: Recent advances in developing small-molecule inhibitors from natural compounds.
Semin Cancer Biol
; 80: 379-390, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33002608
2.
Prediction of Drug-Drug Interactions with Ensartinib as a Time-Dependent CYP3A Inhibitor Using Physiologically Based Pharmacokinetic Model.
Drug Metab Dispos
; 51(11): 1515-1526, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37643879
3.
Foretinib Is Effective against Triple-Negative Breast Cancer Cells MDA-MB-231 In Vitro and In Vivo by Down-Regulating p-MET/HGF Signaling.
Int J Mol Sci
; 24(1)2023 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36614199
4.
Pharmacokinetics of Novel Furoxan/Coumarin Hybrids in Rats Using LC-MS/MS Method and Physiologically Based Pharmacokinetic Model.
Molecules
; 28(2)2023 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36677893
5.
Extracellular vesicles, the cornerstone of next-generation cancer diagnosis?
Semin Cancer Biol
; 74: 105-120, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33989735
6.
An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma.
Proc Natl Acad Sci U S A
; 116(46): 23264-23273, 2019 11 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31662475
7.
Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach.
Int J Mol Sci
; 23(9)2022 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35562875
8.
Utilization of Physiologically Based Pharmacokinetic Modeling in Pharmacokinetic Study of Natural Medicine: An Overview.
Molecules
; 27(24)2022 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36557804
9.
Investigating the interaction between nifedipine- and ritonavir-containing antiviral regimens: A physiologically based pharmacokinetic/pharmacodynamic analysis.
Br J Clin Pharmacol
; 87(7): 2790-2806, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33269470
10.
Intracellular vincristine levels in lymphoblasts affect treatment outcome in childhood B-lymphoblastic leukaemia: Ma-Spore ALL 2010 study.
Br J Clin Pharmacol
; 87(4): 1990-1999, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33037681
11.
Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling.
Arch Toxicol
; 95(5): 1683-1701, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33713150
12.
Simulation of the In Vivo Fate of Polymeric Nanoparticles Traced by Environment-Responsive Near-Infrared Dye: A Physiologically Based Pharmacokinetic Modelling Approach.
Molecules
; 26(5)2021 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-33652827
13.
Development, In Vitro and In Vivo Evaluation of Racecadotril Orodispersible Films for Pediatric Use.
AAPS PharmSciTech
; 22(1): 15, 2021 Jan 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33389269
14.
A unique CDK4/6 inhibitor: Current and future therapeutic strategies of abemaciclib.
Pharmacol Res
; 156: 104686, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32068118
15.
Mechanistic examination of methimazole-induced hepatotoxicity in patients with Grave's disease: a metabolomic approach.
Arch Toxicol
; 94(1): 231-244, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31740989
16.
A Biological Retina Inspired Tone Mapping Processor for High-Speed and Energy-Efficient Image Enhancement.
Sensors (Basel)
; 20(19)2020 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33007833
17.
Evaluation of the Impacts of Formulation Parameters on the Pharmacokinetics and Bioequivalence of Risperidone Orodispersible Film: a Physiologically Based Pharmacokinetic Modeling Approach.
AAPS PharmSciTech
; 21(7): 245, 2020 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32856178
18.
Novel in vitro dynamic metabolic system for predicting the human pharmacokinetics of tolbutamide.
Acta Pharmacol Sin
; 39(9): 1522-1532, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29644999
19.
Establishment and assessment of a novel in vitro bio-PK/PD system in predicting the in vivo pharmacokinetics and pharmacodynamics of cyclophosphamide.
Xenobiotica
; 48(4): 368-375, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28532263
20.
Application of a New Dynamic Model to Predict the In Vitro Intrinsic Clearance of Tolbutamide Using Rat Microsomes Encapsulated in a Fab Hydrogel.
Drug Metab Dispos
; 44(1): 40-9, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26467766